Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

TY - JOUR

T1 - Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

AU - Kreft, Marko

AU - Bak, Lasse Kristoffer

AU - Waagepetersen, Helle S

AU - Schousboe, Arne

N1 - art:e00086

PY - 2012

Y1 - 2012

N2 - Astrocytes are key players in brain function; they are intimately involved in neuronal signalling processes and their metabolism is tightly coupled to that of neurons. In the present review, we will be concerned with a discussion of aspects of astrocyte metabolism, including energy-generating pathways and amino acid homoeostasis. A discussion of the impact that uptake of neurotransmitter glutamate may have on these pathways is included along with a section on metabolic compartmentation.

AB - Astrocytes are key players in brain function; they are intimately involved in neuronal signalling processes and their metabolism is tightly coupled to that of neurons. In the present review, we will be concerned with a discussion of aspects of astrocyte metabolism, including energy-generating pathways and amino acid homoeostasis. A discussion of the impact that uptake of neurotransmitter glutamate may have on these pathways is included along with a section on metabolic compartmentation.

U2 - 10.1042/AN20120007

DO - 10.1042/AN20120007

M3 - Review

C2 - 22435484

SN - 1759-0914

VL - 4

SP - 187

JO - A S N Neuro

JF - A S N Neuro

IS - 3

ER -