Antithyroideaantistof hos to patienter med subakut dementiel udvikling, ataksi og myoklonus

Translated title of the contribution: Anti-thyroid antibodies in two patients with subacute dementia, ataxia, and myoclonus

Daniel Kondziella, Klaus Hansen, Teresa Gonzalez, Peter Gideon, Ingelise Christiansen, Finn Sellebjerg

3 Citations (Scopus)

Abstract

Hashimoto encephalitis (HE) is a steroid-responsive autoimmune encephalitis with anti-thyroid antibodies; Creutzfeldt-Jakob disease (CJD) is a prion disease. Both disorders can have a similar clinical presentation. Two women, 67 and 63 year-old, with subacute dementia, ataxia, myoclonus and positive antithyroid antibodies were given oral steroids. Whereas one progressively declined and had histopathologically proven CJD, the other made a complete recovery and was diagnosed with HE. Anti-thyroid antibodies can occur in CJD, but when present in a patient with subacute dementia, ataxia and myoclonus, a steroid trial always seems indicated.
Translated title of the contributionAnti-thyroid antibodies in two patients with subacute dementia, ataxia, and myoclonus
Original languageDanish
JournalUgeskrift for Laeger
Volume174
Issue number9
Pages (from-to)577-9
Number of pages3
ISSN0041-5782
Publication statusPublished - 2012

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