Antioxidanter som kemoprævention mod fotokarcinogenese

Kaveh Borhani-Khomani; Rikke Holmgaard

Antioxidanter som kemoprævention mod fotokarcinogenese

Translated title of the contribution: Chemoprevention of photocarcinogenesis using antioxidants

Kaveh Borhani-Khomani, Rikke Holmgaard

Department of Clinical Medicine

Abstract

The skin is constantly exposed to reactive oxygen species (ROS) from both endogenous and exogenous sources. Ultraviolet irradiation is a well-known contributor of photocarcinogenesis and photoaging, as it - among other things - promotes the production of ROS which damage nucleic acids, proteins and lipids. Topical or oral administration of antioxidants is presumed to counteract the damaging effects of ROS to the skin, thus potentially lowering the risk of skin cancers and skin aging. We review the current literature on chemoprevention of photocarcinogenesis using antioxidants.

Translated title of the contribution	Chemoprevention of photocarcinogenesis using antioxidants
Original language	Danish
Article number	V09160633
Journal	Ugeskrift for Læger
Volume	179
Number of pages	4
ISSN	0041-5782
Publication status	Published - 2017

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Cite this

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title = "Antioxidanter som kemopr{\ae}vention mod fotokarcinogenese",

abstract = "The skin is constantly exposed to reactive oxygen species (ROS) from both endogenous and exogenous sources. Ultraviolet irradiation is a well-known contributor of photocarcinogenesis and photoaging, as it - among other things - promotes the production of ROS which damage nucleic acids, proteins and lipids. Topical or oral administration of antioxidants is presumed to counteract the damaging effects of ROS to the skin, thus potentially lowering the risk of skin cancers and skin aging. We review the current literature on chemoprevention of photocarcinogenesis using antioxidants.",

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year = "2017",

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AU - Holmgaard, Rikke

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N2 - The skin is constantly exposed to reactive oxygen species (ROS) from both endogenous and exogenous sources. Ultraviolet irradiation is a well-known contributor of photocarcinogenesis and photoaging, as it - among other things - promotes the production of ROS which damage nucleic acids, proteins and lipids. Topical or oral administration of antioxidants is presumed to counteract the damaging effects of ROS to the skin, thus potentially lowering the risk of skin cancers and skin aging. We review the current literature on chemoprevention of photocarcinogenesis using antioxidants.

AB - The skin is constantly exposed to reactive oxygen species (ROS) from both endogenous and exogenous sources. Ultraviolet irradiation is a well-known contributor of photocarcinogenesis and photoaging, as it - among other things - promotes the production of ROS which damage nucleic acids, proteins and lipids. Topical or oral administration of antioxidants is presumed to counteract the damaging effects of ROS to the skin, thus potentially lowering the risk of skin cancers and skin aging. We review the current literature on chemoprevention of photocarcinogenesis using antioxidants.

M3 - Tidsskriftartikel

C2 - 28074764

SN - 0041-5782

VL - 179

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

M1 - V09160633

ER -

Antioxidanter som kemoprævention mod fotokarcinogenese

Abstract

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