Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

Kevin G. Daly; Pierpaolo Maisano Delser; Victoria E. Mullin; Amelie Scheu; Valeria Mattiangeli; Matthew D. Teasdale; Andrew J. Hare; Joachim Burger; Marta Pereira Verdugo; Matthew J. Collins; Ron Kehati; Cevdet Merih Erek; Guy Bar-oz; François Pompanon; Tristan Cumer; Canan Çakırlar; Azadeh Fatemeh Mohaseb; Delphine Decruyenaere; Hossein Davoudi; Özlem Çevik; Gary Rollefson; Jean-denis Vigne; Roya Khazaeli; Homa Fathi; Sanaz Beizaee Doost; Roghayeh Rahimi Sorkhani; Ali Akbar Vahdati; Eberhard W. Sauer; Hossein Azizi Kharanaghi; Sepideh Maziar; Boris Gasparian; Ron Pinhasi; Louise Martin; David Orton; Benjamin S. Arbuckle; Norbert Benecke; Andrea Manica; Liora Kolska Horwitz; Marjan Mashkour; Daniel G. Bradley

doi:10.1126/science.aas9411

Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

Kevin G. Daly, Pierpaolo Maisano Delser, Victoria E. Mullin, Amelie Scheu, Valeria Mattiangeli, Matthew D. Teasdale, Andrew J. Hare, Joachim Burger, Marta Pereira Verdugo, Matthew J. Collins, Ron Kehati, Cevdet Merih Erek, Guy Bar-oz, François Pompanon, Tristan Cumer, Canan Çakırlar, Azadeh Fatemeh Mohaseb, Delphine Decruyenaere, Hossein Davoudi, Özlem ÇevikGary Rollefson, Jean-denis Vigne, Roya Khazaeli, Homa Fathi, Sanaz Beizaee Doost, Roghayeh Rahimi Sorkhani, Ali Akbar Vahdati, Eberhard W. Sauer, Hossein Azizi Kharanaghi, Sepideh Maziar, Boris Gasparian, Ron Pinhasi, Louise Martin, David Orton, Benjamin S. Arbuckle, Norbert Benecke, Andrea Manica, Liora Kolska Horwitz, Marjan Mashkour, Daniel G. Bradley

41 Citations (Scopus)

Abstract

Current genetic data are equivocal as to whether goat domestication occurred multiple times or was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage) from Paleolithic to Medieval contexts throughout the Near East. Our findings demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process that resulted in genetically and geographically distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa, and Europe. We also detect early selection for pigmentation, stature, reproduction, milking, and response to dietary change, providing 8000-year-old evidence for human agency in molding genome variation within a partner species.

Original language	English
Journal	Science
Volume	361
Issue number	6397
Pages (from-to)	85-88
ISSN	0036-8075
DOIs	https://doi.org/10.1126/science.aas9411
Publication status	Published - 6 Jul 2018

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Daly, K. G., Maisano Delser, P., Mullin, V. E., Scheu, A., Mattiangeli, V., Teasdale, M. D., Hare, A. J., Burger, J., Verdugo, M. P., Collins, M. J., Kehati, R., Erek, C. M., Bar-oz, G., Pompanon, F., Cumer, T., Çakırlar, C., Mohaseb, A. F., Decruyenaere, D., Davoudi, H., ... Bradley, D. G. (2018). Ancient goat genomes reveal mosaic domestication in the Fertile Crescent. Science, 361(6397), 85-88. https://doi.org/10.1126/science.aas9411

Daly, KG, Maisano Delser, P, Mullin, VE, Scheu, A, Mattiangeli, V, Teasdale, MD, Hare, AJ, Burger, J, Verdugo, MP, Collins, MJ, Kehati, R, Erek, CM, Bar-oz, G, Pompanon, F, Cumer, T, Çakırlar, C, Mohaseb, AF, Decruyenaere, D, Davoudi, H, Çevik, Ö, Rollefson, G, Vigne, J, Khazaeli, R, Fathi, H, Doost, SB, Rahimi Sorkhani, R, Vahdati, AA, Sauer, EW, Azizi Kharanaghi, H, Maziar, S, Gasparian, B, Pinhasi, R, Martin, L, Orton, D, Arbuckle, BS, Benecke, N, Manica, A, Horwitz, LK, Mashkour, M & Bradley, DG 2018, 'Ancient goat genomes reveal mosaic domestication in the Fertile Crescent', Science, vol. 361, no. 6397, pp. 85-88. https://doi.org/10.1126/science.aas9411

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title = "Ancient goat genomes reveal mosaic domestication in the Fertile Crescent",

abstract = "Current genetic data are equivocal as to whether goat domestication occurred multiple times or was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage) from Paleolithic to Medieval contexts throughout the Near East. Our findings demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process that resulted in genetically and geographically distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa, and Europe. We also detect early selection for pigmentation, stature, reproduction, milking, and response to dietary change, providing 8000-year-old evidence for human agency in molding genome variation within a partner species.",

author = "Daly, {Kevin G.} and {Maisano Delser}, Pierpaolo and Mullin, {Victoria E.} and Amelie Scheu and Valeria Mattiangeli and Teasdale, {Matthew D.} and Hare, {Andrew J.} and Joachim Burger and Verdugo, {Marta Pereira} and Collins, {Matthew J.} and Ron Kehati and Erek, {Cevdet Merih} and Guy Bar-oz and Fran{\c c}ois Pompanon and Tristan Cumer and Canan {\c C}akırlar and Mohaseb, {Azadeh Fatemeh} and Delphine Decruyenaere and Hossein Davoudi and {\"O}zlem {\c C}evik and Gary Rollefson and Jean-denis Vigne and Roya Khazaeli and Homa Fathi and Doost, {Sanaz Beizaee} and {Rahimi Sorkhani}, Roghayeh and Vahdati, {Ali Akbar} and Sauer, {Eberhard W.} and {Azizi Kharanaghi}, Hossein and Sepideh Maziar and Boris Gasparian and Ron Pinhasi and Louise Martin and David Orton and Arbuckle, {Benjamin S.} and Norbert Benecke and Andrea Manica and Horwitz, {Liora Kolska} and Marjan Mashkour and Bradley, {Daniel G.}",

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AU - Maisano Delser, Pierpaolo

AU - Mullin, Victoria E.

AU - Scheu, Amelie

AU - Mattiangeli, Valeria

AU - Teasdale, Matthew D.

AU - Hare, Andrew J.

AU - Burger, Joachim

AU - Verdugo, Marta Pereira

AU - Collins, Matthew J.

AU - Kehati, Ron

AU - Erek, Cevdet Merih

AU - Bar-oz, Guy

AU - Pompanon, François

AU - Cumer, Tristan

AU - Çakırlar, Canan

AU - Mohaseb, Azadeh Fatemeh

AU - Decruyenaere, Delphine

AU - Davoudi, Hossein

AU - Çevik, Özlem

AU - Rollefson, Gary

AU - Vigne, Jean-denis

AU - Khazaeli, Roya

AU - Fathi, Homa

AU - Doost, Sanaz Beizaee

AU - Rahimi Sorkhani, Roghayeh

AU - Vahdati, Ali Akbar

AU - Sauer, Eberhard W.

AU - Azizi Kharanaghi, Hossein

AU - Maziar, Sepideh

AU - Gasparian, Boris

AU - Pinhasi, Ron

AU - Martin, Louise

AU - Orton, David

AU - Arbuckle, Benjamin S.

AU - Benecke, Norbert

AU - Manica, Andrea

AU - Horwitz, Liora Kolska

AU - Mashkour, Marjan

AU - Bradley, Daniel G.

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N2 - Current genetic data are equivocal as to whether goat domestication occurred multiple times or was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage) from Paleolithic to Medieval contexts throughout the Near East. Our findings demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process that resulted in genetically and geographically distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa, and Europe. We also detect early selection for pigmentation, stature, reproduction, milking, and response to dietary change, providing 8000-year-old evidence for human agency in molding genome variation within a partner species.

AB - Current genetic data are equivocal as to whether goat domestication occurred multiple times or was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage) from Paleolithic to Medieval contexts throughout the Near East. Our findings demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process that resulted in genetically and geographically distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa, and Europe. We also detect early selection for pigmentation, stature, reproduction, milking, and response to dietary change, providing 8000-year-old evidence for human agency in molding genome variation within a partner species.

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SP - 85

EP - 88

JO - Science

JF - Science

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ER -

Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

Abstract

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