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An invertebrate model for CNS drug discovery: transcriptomic and functional analysis of a mammalian P-glycoprotein ortholog
Sonia Al-Qadi, Morten Schiøtt, Steen Honoré Hansen, Peter Aadal Nielsen, Lassina Badolo
Ecology and Evolution
4
Citations (Scopus)
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Dive into the research topics of 'An invertebrate model for CNS drug discovery: transcriptomic and functional analysis of a mammalian P-glycoprotein ortholog'. Together they form a unique fingerprint.
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Medicine & Life Sciences
Central Nervous System Agents
73%
Grasshoppers
61%
Invertebrates
59%
ATP Binding Cassette Transporter, Subfamily B, Member 1
56%
Drug Discovery
53%
Vertebrates
23%
ATP-Binding Cassette Transporters
20%
Brain
16%
Blood-Brain Barrier
16%
Kinetics
12%
Drosophila melanogaster
9%
Insecta
9%
Gene Expression Profiling
8%
Amino Acid Sequence
7%
Permeability
7%
History
6%
Proteins
6%
Cell Line
5%
In Vitro Techniques
3%
Pharmaceutical Preparations
3%
Genes
3%
Chemical Compounds
Central Nervous System Drug
100%
Central Nervous System Agent
45%
High Throughput Screening
27%
Pump
24%
Amino Acid Sequence
23%
Protein
21%
Permeability
20%
Drug
13%