An international study of the quality of life of adult patients treated with home parenteral nutrition

Home Artificial Nutrition and Chronic Intestinal Failure Special Interest Group of the European Society for Clinical Nutrition and Metabolism (ESPEN)

doi:10.1016/j.clnu.2018.07.024

An international study of the quality of life of adult patients treated with home parenteral nutrition

Home Artificial Nutrition and Chronic Intestinal Failure Special Interest Group of the European Society for Clinical Nutrition and Metabolism (ESPEN)

Department of Clinical Medicine

19 Citations (Scopus)

Abstract

Background & aims: Home parenteral nutrition-quality of life (HPN-QOL ^© ) is a self-assessment tool for the measurement of QOL in patients on HPN. The aims of this study were: to re-assess the basic psychometric properties of the HPN-QOL ^© in a multinational sample of adult patients; to provide a description of QOL dimensions by short and long HPN treatment duration; to explore clinical factors potentially associated to QOL scores. Methods: Patients (n = 699) from 14 countries completed the HPN-QOL ^© . The questionnaires were analysed to evaluate data completeness, convergent/discriminant validity and internal-consistency reliability. The association of overall QOL and HPN treatment duration as well as other clinical factors were investigated using multivariable linear regression models. Results: The analysis of the multitrait-scaling and internal consistency indicates a good fit with the questionnaire structure for most items. Item discriminant validity correlation was satisfactory and psychometric evaluation of the HPN-QOL ^© in the different English, French and Italian language patient sub-groups confirmed psychometric equivalence of the three questionnaire versions. The results of the multivariable linear regression showed that QOL scores were significantly associated with HPN duration (better in long-term), underlying disease (better in Crohn's disease and mesenteric ischaemia) and living status (worse in living alone) and, after adjusting for the other factors, with the number of days of HPN infusion per week. Conclusions: The HPN-QOL ^© , is a valid tool for measurement of QOL in patients on HPN, to be used in the clinical practice as well as in research.

Original language	English
Journal	Clinical Nutrition
Volume	38
Issue number	4
Pages (from-to)	1788-1796
ISSN	0261-5614
DOIs	https://doi.org/10.1016/j.clnu.2018.07.024
Publication status	Published - Aug 2019

Keywords

Home parenteral nutrition
Intestinal failure
Patient reported outcomes
Quality of life

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10.1016/j.clnu.2018.07.024

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An international study of the quality of life of adult patients treated with home parenteral nutrition. / Home Artificial Nutrition and Chronic Intestinal Failure Special Interest Group of the European Society for Clinical Nutrition and Metabolism (ESPEN).
In: Clinical Nutrition, Vol. 38, No. 4, 08.2019, p. 1788-1796.

Research output: Contribution to journal › Journal article › Research › peer-review

@article{a4c5f6cd766a42cca14d3ecbd8f8184f,

title = "An international study of the quality of life of adult patients treated with home parenteral nutrition",

abstract = " Background & aims: Home parenteral nutrition-quality of life (HPN-QOL {\textcopyright} ) is a self-assessment tool for the measurement of QOL in patients on HPN. The aims of this study were: to re-assess the basic psychometric properties of the HPN-QOL {\textcopyright} in a multinational sample of adult patients; to provide a description of QOL dimensions by short and long HPN treatment duration; to explore clinical factors potentially associated to QOL scores. Methods: Patients (n = 699) from 14 countries completed the HPN-QOL {\textcopyright} . The questionnaires were analysed to evaluate data completeness, convergent/discriminant validity and internal-consistency reliability. The association of overall QOL and HPN treatment duration as well as other clinical factors were investigated using multivariable linear regression models. Results: The analysis of the multitrait-scaling and internal consistency indicates a good fit with the questionnaire structure for most items. Item discriminant validity correlation was satisfactory and psychometric evaluation of the HPN-QOL {\textcopyright} in the different English, French and Italian language patient sub-groups confirmed psychometric equivalence of the three questionnaire versions. The results of the multivariable linear regression showed that QOL scores were significantly associated with HPN duration (better in long-term), underlying disease (better in Crohn's disease and mesenteric ischaemia) and living status (worse in living alone) and, after adjusting for the other factors, with the number of days of HPN infusion per week. Conclusions: The HPN-QOL {\textcopyright} , is a valid tool for measurement of QOL in patients on HPN, to be used in the clinical practice as well as in research. ",

keywords = "Home parenteral nutrition, Intestinal failure, Patient reported outcomes, Quality of life",

author = "Baxter, {Janet P.} and Fayers, {Peter M.} and Federico Bozzetti and Darlene Kelly and Francisca Joly and Geert Wanten and Cora Jonkers and Cristina Cuerda and {van Gossum}, Andre and Stanislaw Klek and Boudreault, {Marie France} and Alain Gilbert and Manon Jobin and Michael Staun and Lyn Gillanders and Alastair Forbes and Margie O'Callaghan and Faedo, {Ceferino Mart{\'i}nez} and Cinzia Brunelli and Luigi Mariani and Loris Pironi and {Home Artificial Nutrition and Chronic Intestinal Failure Special Interest Group of the European Society for Clinical Nutrition and Metabolism (ESPEN)}",

year = "2019",

month = aug,

doi = "10.1016/j.clnu.2018.07.024",

language = "English",

volume = "38",

pages = "1788--1796",

journal = "Clinical Nutrition",

issn = "0261-5614",

publisher = "Elsevier",

number = "4",

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TY - JOUR

T1 - An international study of the quality of life of adult patients treated with home parenteral nutrition

AU - Baxter, Janet P.

AU - Fayers, Peter M.

AU - Bozzetti, Federico

AU - Kelly, Darlene

AU - Joly, Francisca

AU - Wanten, Geert

AU - Jonkers, Cora

AU - Cuerda, Cristina

AU - van Gossum, Andre

AU - Klek, Stanislaw

AU - Boudreault, Marie France

AU - Gilbert, Alain

AU - Jobin, Manon

AU - Staun, Michael

AU - Gillanders, Lyn

AU - Forbes, Alastair

AU - O'Callaghan, Margie

AU - Faedo, Ceferino Martínez

AU - Brunelli, Cinzia

AU - Mariani, Luigi

AU - Pironi, Loris

AU - Home Artificial Nutrition and Chronic Intestinal Failure Special Interest Group of the European Society for Clinical Nutrition and Metabolism (ESPEN)

PY - 2019/8

Y1 - 2019/8

N2 - Background & aims: Home parenteral nutrition-quality of life (HPN-QOL © ) is a self-assessment tool for the measurement of QOL in patients on HPN. The aims of this study were: to re-assess the basic psychometric properties of the HPN-QOL © in a multinational sample of adult patients; to provide a description of QOL dimensions by short and long HPN treatment duration; to explore clinical factors potentially associated to QOL scores. Methods: Patients (n = 699) from 14 countries completed the HPN-QOL © . The questionnaires were analysed to evaluate data completeness, convergent/discriminant validity and internal-consistency reliability. The association of overall QOL and HPN treatment duration as well as other clinical factors were investigated using multivariable linear regression models. Results: The analysis of the multitrait-scaling and internal consistency indicates a good fit with the questionnaire structure for most items. Item discriminant validity correlation was satisfactory and psychometric evaluation of the HPN-QOL © in the different English, French and Italian language patient sub-groups confirmed psychometric equivalence of the three questionnaire versions. The results of the multivariable linear regression showed that QOL scores were significantly associated with HPN duration (better in long-term), underlying disease (better in Crohn's disease and mesenteric ischaemia) and living status (worse in living alone) and, after adjusting for the other factors, with the number of days of HPN infusion per week. Conclusions: The HPN-QOL © , is a valid tool for measurement of QOL in patients on HPN, to be used in the clinical practice as well as in research.

AB - Background & aims: Home parenteral nutrition-quality of life (HPN-QOL © ) is a self-assessment tool for the measurement of QOL in patients on HPN. The aims of this study were: to re-assess the basic psychometric properties of the HPN-QOL © in a multinational sample of adult patients; to provide a description of QOL dimensions by short and long HPN treatment duration; to explore clinical factors potentially associated to QOL scores. Methods: Patients (n = 699) from 14 countries completed the HPN-QOL © . The questionnaires were analysed to evaluate data completeness, convergent/discriminant validity and internal-consistency reliability. The association of overall QOL and HPN treatment duration as well as other clinical factors were investigated using multivariable linear regression models. Results: The analysis of the multitrait-scaling and internal consistency indicates a good fit with the questionnaire structure for most items. Item discriminant validity correlation was satisfactory and psychometric evaluation of the HPN-QOL © in the different English, French and Italian language patient sub-groups confirmed psychometric equivalence of the three questionnaire versions. The results of the multivariable linear regression showed that QOL scores were significantly associated with HPN duration (better in long-term), underlying disease (better in Crohn's disease and mesenteric ischaemia) and living status (worse in living alone) and, after adjusting for the other factors, with the number of days of HPN infusion per week. Conclusions: The HPN-QOL © , is a valid tool for measurement of QOL in patients on HPN, to be used in the clinical practice as well as in research.

KW - Home parenteral nutrition

KW - Intestinal failure

KW - Patient reported outcomes

KW - Quality of life

U2 - 10.1016/j.clnu.2018.07.024

DO - 10.1016/j.clnu.2018.07.024

M3 - Journal article

C2 - 30115461

AN - SCOPUS:85051406224

SN - 0261-5614

VL - 38

SP - 1788

EP - 1796

JO - Clinical Nutrition

JF - Clinical Nutrition

IS - 4

ER -

An international study of the quality of life of adult patients treated with home parenteral nutrition

Abstract

Keywords

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