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Advances in lipid-lowering therapy through gene-silencing technologies
Børge G. Nordestgaard
, Stephen J. Nicholls, Anne Langsted, Kausik K. Ray,
Anne Tybjærg-Hansen
Department of Clinical Medicine
47
Citations (Scopus)
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Keyphrases
Lipid-lowering Therapy
100%
Cardiovascular Disease
100%
Lipoproteins
100%
Gene Silencing
100%
Acute Pancreatitis
66%
Adverse Effects
66%
Protein Production
33%
Clinical High Risk
33%
Injection Site Reaction
33%
Remnant Lipoproteins
33%
Liver Cells
33%
Flu-like
33%
Plasma Lipoproteins
33%
Long-term Safety
33%
Lipoprotein Levels
33%
Drug Dosing
33%
RNA Transcripts
33%
Unmet Medical Need
33%
ANGPTL3
33%
Antisense Oligonucleotides
33%
Blood Platelet Count
33%
Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9)
33%
Target Molecule
33%
Triglyceride-rich Lipoproteins
33%
New Therapies
33%
Small Interfering RNA (siRNA)
33%
Protein Drug
33%
Plasma Parameters
33%
Disease Reduction
33%
Treatment Opportunity
33%
Biochemistry, Genetics and Molecular Biology
Lipid
100%
Lipoprotein
100%
Gene Inactivation
100%
Messenger RNA
20%
Oligonucleotide
20%
Small Interfering RNA
20%
Platelet Count
20%
Targeting Protein
20%
Lipoprotein Blood Level
20%
Low Drug Dose
20%
Antisense
20%
Blood Level
20%
Triglyceride-Rich Lipoprotein
20%
PCSK9
20%
Pharmacology, Toxicology and Pharmaceutical Science
Lipoprotein
100%
Cardiovascular Disease
50%
Acute Pancreatitis
33%
Flu Like Syndrome
16%
Small Interfering RNA
16%
Drug Dose
16%
Triacylglycerol
16%
Messenger RNA
16%
Lipoprotein A
16%
Injection Site Reaction
16%
Antisense Oligonucleotide
16%