Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes

Matthias Manfred Herth; Sebastian Leth-Petersen; Szabolcs Lehel; Martin Hansen; Nic Gillings; Jacob Madsen; Jesper Langgaard Kristensen

Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes

Matthias Manfred Herth, Sebastian Leth-Petersen, Szabolcs Lehel, Martin Hansen, Nic Gillings, Jacob Madsen, Jesper Langgaard Kristensen

Department of Drug Design and Pharmacology

9 Citations (Scopus)

Abstract

We report, herein, a simple and efficient labelling strategy for multiple PET tracer preparation using a common intermediate, which has the potential to accelerate preclinical PET radiotracer screening. This procedure was applied to and compared with a previously published labelling strategy illustrating the advantages of this newly developed combinatorial approach. This journal is

Original language	Danish
Journal	R S C Advances
Volume	41
Pages (from-to)	21347-21350
Number of pages	4
ISSN	2046-2069
Publication status	Published - 2014

Cite this

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title = "Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes",

abstract = "We report, herein, a simple and efficient labelling strategy for multiple PET tracer preparation using a common intermediate, which has the potential to accelerate preclinical PET radiotracer screening. This procedure was applied to and compared with a previously published labelling strategy illustrating the advantages of this newly developed combinatorial approach. This journal is",

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T1 - Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes

AU - Herth, Matthias Manfred

AU - Leth-Petersen, Sebastian

AU - Lehel, Szabolcs

AU - Hansen, Martin

AU - Gillings, Nic

AU - Madsen, Jacob

AU - Kristensen, Jesper Langgaard

PY - 2014

Y1 - 2014

N2 - We report, herein, a simple and efficient labelling strategy for multiple PET tracer preparation using a common intermediate, which has the potential to accelerate preclinical PET radiotracer screening. This procedure was applied to and compared with a previously published labelling strategy illustrating the advantages of this newly developed combinatorial approach. This journal is

AB - We report, herein, a simple and efficient labelling strategy for multiple PET tracer preparation using a common intermediate, which has the potential to accelerate preclinical PET radiotracer screening. This procedure was applied to and compared with a previously published labelling strategy illustrating the advantages of this newly developed combinatorial approach. This journal is

M3 - Tidsskriftartikel

SN - 2046-2069

VL - 41

SP - 21347

EP - 21350

JO - RSC Advances

JF - RSC Advances

ER -