Absolute configuration and antiprotozoal activity of minquartynoic acid

H B Rasmussen; Søren Brøgger Christensen; L P Kvist; A Kharazmi; A G Huansi

Absolute configuration and antiprotozoal activity of minquartynoic acid

H B Rasmussen, Søren Brøgger Christensen, L P Kvist, A Kharazmi, A G Huansi

Centre for Medical Parasitology

29 Citations (Scopus)

Abstract

Minquartynoic acid (1) was isolated as an antimalarial and antileishmanial constituent of the Peruvian tree Minquartia guianensis and its absolute configuration at C-17 established to be (+)-S through conversion to the known (+)-(S)-17-hydroxystearic acid (2) and confirmed using Mosher's method.

Original language	English
Journal	Journal of Natural Products
Volume	63
Issue number	9
Pages (from-to)	1295-6
Number of pages	1
ISSN	0163-3864
Publication status	Published - 2000

Cite this

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title = "Absolute configuration and antiprotozoal activity of minquartynoic acid",

abstract = "Minquartynoic acid (1) was isolated as an antimalarial and antileishmanial constituent of the Peruvian tree Minquartia guianensis and its absolute configuration at C-17 established to be (+)-S through conversion to the known (+)-(S)-17-hydroxystearic acid (2) and confirmed using Mosher's method.",

author = "Rasmussen, {H B} and Christensen, {S{\o}ren Br{\o}gger} and Kvist, {L P} and A Kharazmi and Huansi, {A G}",

note = "Keywords: Alkynes; Animals; Antiprotozoal Agents; Cell Division; Fatty Acids, Unsaturated; Humans; Leishmania major; Lymphocytes; Molecular Structure; Plasmodium falciparum; Polyacetylenes",

year = "2000",

language = "English",

volume = "63",

pages = "1295--6",

journal = "Journal of Natural Products",

issn = "0163-3864",

publisher = "American Chemical Society",

number = "9",

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TY - JOUR

T1 - Absolute configuration and antiprotozoal activity of minquartynoic acid

AU - Rasmussen, H B

AU - Christensen, Søren Brøgger

AU - Kvist, L P

AU - Kharazmi, A

AU - Huansi, A G

N1 - Keywords: Alkynes; Animals; Antiprotozoal Agents; Cell Division; Fatty Acids, Unsaturated; Humans; Leishmania major; Lymphocytes; Molecular Structure; Plasmodium falciparum; Polyacetylenes

PY - 2000

Y1 - 2000

N2 - Minquartynoic acid (1) was isolated as an antimalarial and antileishmanial constituent of the Peruvian tree Minquartia guianensis and its absolute configuration at C-17 established to be (+)-S through conversion to the known (+)-(S)-17-hydroxystearic acid (2) and confirmed using Mosher's method.

AB - Minquartynoic acid (1) was isolated as an antimalarial and antileishmanial constituent of the Peruvian tree Minquartia guianensis and its absolute configuration at C-17 established to be (+)-S through conversion to the known (+)-(S)-17-hydroxystearic acid (2) and confirmed using Mosher's method.

M3 - Journal article

C2 - 11000043

SN - 0163-3864

VL - 63

SP - 1295

EP - 1296

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 9

ER -

Absolute configuration and antiprotozoal activity of minquartynoic acid

Abstract

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