Abdominal wall reconstruction for large incisional hernia restores expiratory lung function

TY - JOUR

T1 - Abdominal wall reconstruction for large incisional hernia restores expiratory lung function

AU - Jensen, Kristian K

AU - Backer, Vibeke

AU - Jorgensen, Lars N

N1 - Copyright © 2016 Elsevier Inc. All rights reserved.

PY - 2017/2/1

Y1 - 2017/2/1

N2 - BACKGROUND: Respiratory complications secondary to intermittent intra-abdominal hypertension and/or atelectasis are common after abdominal wall reconstruction for large incisional hernias. It is unknown if the respiratory function of this patient group is affected long term or impairs activities of daily living. We hypothesized that abdominal wall reconstruction for large incisional hernia would not lead to improved, long-term pulmonary function or respiratory quality of life.METHODS: Eighteen patients undergoing open abdominal wall reconstruction with mesh for a large incisional hernia (horizontal fascial defect width >10 cm) were compared with 18 patients with an intact abdominal wall who underwent colorectal resection. Patients were examined pre- and 1-year postoperatively. Examined measures included forced vital capacity, forced expiratory volume in first second, peak expiratory flow, maximal in- and expiratory mouth pressure, and 2 validated questionnaires on respiratory quality of life. In order to decrease heterogeneity, objectively examined parameters were presented relative to the predicted values, which were normality adjusted pulmonary measures.RESULTS: At 1-year follow-up, the abdominal wall reconstruction group showed significant improvement in percent predicted peak expiratory flow and maximal expiratory mouth pressure, whereas all other measurements of lung function remained unchanged. Respiratory quality of life did not change significantly. Patients who underwent abdominal wall reconstruction showed a significantly greater improvement of percent predicted peak expiratory flow compared with patients undergoing colorectal resection.CONCLUSION: Abdominal wall reconstruction for large incisional hernia improved long-term expiratory lung function. Respiratory quality of life did not change significantly after abdominal wall reconstruction.

AB - BACKGROUND: Respiratory complications secondary to intermittent intra-abdominal hypertension and/or atelectasis are common after abdominal wall reconstruction for large incisional hernias. It is unknown if the respiratory function of this patient group is affected long term or impairs activities of daily living. We hypothesized that abdominal wall reconstruction for large incisional hernia would not lead to improved, long-term pulmonary function or respiratory quality of life.METHODS: Eighteen patients undergoing open abdominal wall reconstruction with mesh for a large incisional hernia (horizontal fascial defect width >10 cm) were compared with 18 patients with an intact abdominal wall who underwent colorectal resection. Patients were examined pre- and 1-year postoperatively. Examined measures included forced vital capacity, forced expiratory volume in first second, peak expiratory flow, maximal in- and expiratory mouth pressure, and 2 validated questionnaires on respiratory quality of life. In order to decrease heterogeneity, objectively examined parameters were presented relative to the predicted values, which were normality adjusted pulmonary measures.RESULTS: At 1-year follow-up, the abdominal wall reconstruction group showed significant improvement in percent predicted peak expiratory flow and maximal expiratory mouth pressure, whereas all other measurements of lung function remained unchanged. Respiratory quality of life did not change significantly. Patients who underwent abdominal wall reconstruction showed a significantly greater improvement of percent predicted peak expiratory flow compared with patients undergoing colorectal resection.CONCLUSION: Abdominal wall reconstruction for large incisional hernia improved long-term expiratory lung function. Respiratory quality of life did not change significantly after abdominal wall reconstruction.

KW - Abdominal Wall/surgery

KW - Aged

KW - Case-Control Studies

KW - Colorectal Surgery/adverse effects

KW - Female

KW - Follow-Up Studies

KW - Herniorrhaphy/adverse effects

KW - Humans

KW - Incisional Hernia/surgery

KW - Male

KW - Middle Aged

KW - Postoperative Complications/diagnosis

KW - Quality of Life

KW - Reconstructive Surgical Procedures/methods

KW - Reference Values

KW - Respiratory Function Tests

KW - Severity of Illness Index

KW - Surgical Mesh

KW - Treatment Outcome

U2 - 10.1016/j.surg.2016.08.015

DO - 10.1016/j.surg.2016.08.015

M3 - Journal article

C2 - 27816206

SN - 0039-6060

VL - 161

SP - 517

EP - 524

JO - Surgery

JF - Surgery

IS - 2

ER -