Abdominal obesity has the highest impact on metabolic profile in an overweight African population

Line Neerup Handlos; Daniel R Witte; David L Mwaniki; Michael K Boit; Beatrice Kilonzo; Henrik Friis; Andreas W Hansen; Knut Borch-Johnsen; Inge Tetens; Dirk Lund Christensen

doi:10.3109/03014460.2012.720279

Abdominal obesity has the highest impact on metabolic profile in an overweight African population

Line Neerup Handlos, Daniel R Witte, David L Mwaniki, Michael K Boit, Beatrice Kilonzo, Henrik Friis, Andreas W Hansen, Knut Borch-Johnsen, Inge Tetens, Dirk Lund Christensen

2 Citations (Scopus)

Abstract

Aim: The aim of this study was to determine the association between different anthropometric parameters and metabolic profile in an overweight, adult, black Kenyan population. Methods: An opportunity sample of 245 overweight adult Kenyans (body mass index (BMI) ≥ 25 kg/m²) was analysed. A score of metabolic profile (metabolic Z-score) was constructed on the basis of levels of plasma lipids, blood pressure, blood glucose and serum insulin. Linear regressions using metabolic Z-score as outcome and six anthropometric variables (waist circumference (WC), hip circumference, visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue, arm fat area and arm muscle area) separately as independent variables were carried out. Results: Mean age of study participants was 42.1 years (SD = 9.6) and 26.5% of the participants were men. The median BMI was 28.6 kg/m² (Q1 = 26.3; Q3 = 31.3). Of the six anthropometric variables tested, WC and VAT thickness had the strongest negative association with the metabolic profile (β = 0.17 (0.09; 0.24) and 0.15 (0.08; 0.23), respectively). Conclusions: WC and VAT thickness were the strongest anthropometric predictors for the metabolic profile in overweight adult Kenyans. WC is useful in clinical practice for the diagnosis of metabolically unhealthy fat accumulation in an African setting.

Original language	English
Journal	Annals of Human Biology
Volume	39
Issue number	6
Pages (from-to)	530-533
Number of pages	4
ISSN	0301-4460
DOIs	https://doi.org/10.3109/03014460.2012.720279
Publication status	Published - Nov 2012

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title = "Abdominal obesity has the highest impact on metabolic profile in an overweight African population",

abstract = "Aim: The aim of this study was to determine the association between different anthropometric parameters and metabolic profile in an overweight, adult, black Kenyan population. Methods: An opportunity sample of 245 overweight adult Kenyans (body mass index (BMI) ≥ 25 kg/m2) was analysed. A score of metabolic profile (metabolic Z-score) was constructed on the basis of levels of plasma lipids, blood pressure, blood glucose and serum insulin. Linear regressions using metabolic Z-score as outcome and six anthropometric variables (waist circumference (WC), hip circumference, visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue, arm fat area and arm muscle area) separately as independent variables were carried out. Results: Mean age of study participants was 42.1 years (SD = 9.6) and 26.5% of the participants were men. The median BMI was 28.6 kg/m2 (Q1 = 26.3; Q3 = 31.3). Of the six anthropometric variables tested, WC and VAT thickness had the strongest negative association with the metabolic profile (β = 0.17 (0.09; 0.24) and 0.15 (0.08; 0.23), respectively). Conclusions: WC and VAT thickness were the strongest anthropometric predictors for the metabolic profile in overweight adult Kenyans. WC is useful in clinical practice for the diagnosis of metabolically unhealthy fat accumulation in an African setting.",

author = "Handlos, {Line Neerup} and Witte, {Daniel R} and Mwaniki, {David L} and Boit, {Michael K} and Beatrice Kilonzo and Henrik Friis and Hansen, {Andreas W} and Knut Borch-Johnsen and Inge Tetens and Christensen, {Dirk Lund}",

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T1 - Abdominal obesity has the highest impact on metabolic profile in an overweight African population

AU - Handlos, Line Neerup

AU - Witte, Daniel R

AU - Mwaniki, David L

AU - Boit, Michael K

AU - Kilonzo, Beatrice

AU - Friis, Henrik

AU - Hansen, Andreas W

AU - Borch-Johnsen, Knut

AU - Tetens, Inge

AU - Christensen, Dirk Lund

N1 - IHE 2012 053

PY - 2012/11

Y1 - 2012/11

N2 - Aim: The aim of this study was to determine the association between different anthropometric parameters and metabolic profile in an overweight, adult, black Kenyan population. Methods: An opportunity sample of 245 overweight adult Kenyans (body mass index (BMI) ≥ 25 kg/m2) was analysed. A score of metabolic profile (metabolic Z-score) was constructed on the basis of levels of plasma lipids, blood pressure, blood glucose and serum insulin. Linear regressions using metabolic Z-score as outcome and six anthropometric variables (waist circumference (WC), hip circumference, visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue, arm fat area and arm muscle area) separately as independent variables were carried out. Results: Mean age of study participants was 42.1 years (SD = 9.6) and 26.5% of the participants were men. The median BMI was 28.6 kg/m2 (Q1 = 26.3; Q3 = 31.3). Of the six anthropometric variables tested, WC and VAT thickness had the strongest negative association with the metabolic profile (β = 0.17 (0.09; 0.24) and 0.15 (0.08; 0.23), respectively). Conclusions: WC and VAT thickness were the strongest anthropometric predictors for the metabolic profile in overweight adult Kenyans. WC is useful in clinical practice for the diagnosis of metabolically unhealthy fat accumulation in an African setting.

AB - Aim: The aim of this study was to determine the association between different anthropometric parameters and metabolic profile in an overweight, adult, black Kenyan population. Methods: An opportunity sample of 245 overweight adult Kenyans (body mass index (BMI) ≥ 25 kg/m2) was analysed. A score of metabolic profile (metabolic Z-score) was constructed on the basis of levels of plasma lipids, blood pressure, blood glucose and serum insulin. Linear regressions using metabolic Z-score as outcome and six anthropometric variables (waist circumference (WC), hip circumference, visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue, arm fat area and arm muscle area) separately as independent variables were carried out. Results: Mean age of study participants was 42.1 years (SD = 9.6) and 26.5% of the participants were men. The median BMI was 28.6 kg/m2 (Q1 = 26.3; Q3 = 31.3). Of the six anthropometric variables tested, WC and VAT thickness had the strongest negative association with the metabolic profile (β = 0.17 (0.09; 0.24) and 0.15 (0.08; 0.23), respectively). Conclusions: WC and VAT thickness were the strongest anthropometric predictors for the metabolic profile in overweight adult Kenyans. WC is useful in clinical practice for the diagnosis of metabolically unhealthy fat accumulation in an African setting.

U2 - 10.3109/03014460.2012.720279

DO - 10.3109/03014460.2012.720279

M3 - Journal article

C2 - 22989146

SN - 0301-4460

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SP - 530

EP - 533

JO - Annals of Human Biology

JF - Annals of Human Biology

IS - 6

ER -

Abdominal obesity has the highest impact on metabolic profile in an overweight African population

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