Abstract
The focus of this review is software for the genotyping of microarray single nucleotide polymorphisms, in particular software for Affymetrix and Illumina arrays. Different statistical principles and ideas have been applied to the construction of genotyping algorithms - for example, likelihood versus Bayesian modelling, and whether to genotype one or all arrays at a time. The release of new arrays is generally followed by new, or updated, algorithms.
| Original language | English |
|---|---|
| Journal | Human Genomics |
| Volume | 5 |
| Issue number | 4 |
| Pages (from-to) | 304-309 |
| Number of pages | 6 |
| ISSN | 1473-9542 |
| Publication status | Published - 1 Jan 2011 |
| Externally published | Yes |
Keywords
- Calling algorithm
- Copy number
- Genotype
- Intensity
- SNP array
- Software