A randomized and double-blind comparison of isradipine and spirapril as monotherapy and in combination on the decline in renal function in patients with chronic renal failure and hypertension

L J Petersen; J R Petersen; U Talleruphuus; M L Møller; S D Ladefoged; J Mehlsen; H A Jensen

A randomized and double-blind comparison of isradipine and spirapril as monotherapy and in combination on the decline in renal function in patients with chronic renal failure and hypertension

L J Petersen, J R Petersen, U Talleruphuus, M L Møller, S D Ladefoged, J Mehlsen, H A Jensen

14 Citations (Scopus)

Abstract

Treatment of hypertension in patients with chronic renal failure has been shown to postpone the decline in renal function. Treatment with an ACE inhibitor has been shown to be superior to conventional antihypertensive treatment, but it is not known how an ACE inhibitor compares to treatment with a calcium channel blocker or to treatment with a combination of these drugs. The aim of the study was to evaluate the rate of decline in GFR in patients with chronic renal failure and hypertension treated with isradipine and spirapril as monotherapy and in combination.

Original language	English
Journal	Clinical Nephrology
Volume	55
Issue number	5
Pages (from-to)	375-83
Number of pages	9
ISSN	0301-0430
Publication status	Published - 1 May 2001

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A randomized and double-blind comparison of isradipine and spirapril as monotherapy and in combination on the decline in renal function in patients with chronic renal failure and hypertension. / Petersen, L J; Petersen, J R; Talleruphuus, U et al.
In: Clinical Nephrology, Vol. 55, No. 5, 01.05.2001, p. 375-83.

Research output: Contribution to journal › Journal article › Research › peer-review

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AU - Talleruphuus, U

AU - Møller, M L

AU - Ladefoged, S D

AU - Mehlsen, J

AU - Jensen, H A

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AB - Treatment of hypertension in patients with chronic renal failure has been shown to postpone the decline in renal function. Treatment with an ACE inhibitor has been shown to be superior to conventional antihypertensive treatment, but it is not known how an ACE inhibitor compares to treatment with a calcium channel blocker or to treatment with a combination of these drugs. The aim of the study was to evaluate the rate of decline in GFR in patients with chronic renal failure and hypertension treated with isradipine and spirapril as monotherapy and in combination.

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JO - Clinical Nephrology

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IS - 5

ER -

A randomized and double-blind comparison of isradipine and spirapril as monotherapy and in combination on the decline in renal function in patients with chronic renal failure and hypertension

Abstract

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