A prospective international Aspergillus terreus survey: an EFISG, ISHAM and ECMM joint study

B Risslegger, T Zoran, M Lackner, M Aigner, F Sánchez-Reus, A Rezusta, A Chowdhary, S J Taj-Aldeen, M C Arendrup, S Oliveri, D P Kontoyiannis, A Alastruey-Izquierdo, K Lagrou, G Lo Cascio, J F Meis, W Buzina, C Farina, M Drogari-Apiranthitou, A Grancini, A M TortoranoB Willinger, A Hamprecht, E Johnson, L Klingspor, V Arsic-Arsenijevic, O A Cornely, J Meletiadis, W Prammer, V Tullio, J-J Vehreschild, L Trovato, R E Lewis, E Segal, P-M Rath, P Hamal, M Rodriguez-Iglesias, E Roilides, S Arikan-Akdagli, A Chakrabarti, A L Colombo, M S Fernández, M T Martin-Gomez, H Badali, G Petrikkos, N Klimko, S M Heimann, J Houbraken, O Uzun, M Edlinger, S de la Fuente, C. Lass-Flörl

24 Citations (Scopus)

Abstract

OBJECTIVES: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections.

METHODS: A total of 370 cases from 21 countries were evaluated.

RESULTS: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L).

CONCLUSIONS: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.

Original languageEnglish
JournalClinical Microbiology and Infection
Volume23
Issue number10
Pages (from-to)776.e1-776.e5
ISSN1198-743X
DOIs
Publication statusPublished - Oct 2017

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