A history of arterial hypertension does not affect mortality in patients hospitalised with congestive heart failure

F Gustafsson; C Torp-Pedersen; M Seibaek; H Burchardt; O Wendelboe Nielsen; L Køber; DIAMOND Study Group

doi:10.1136/hrt.2005.080572

A history of arterial hypertension does not affect mortality in patients hospitalised with congestive heart failure

F Gustafsson, C Torp-Pedersen, M Seibaek, H Burchardt, O Wendelboe Nielsen, L Køber, DIAMOND Study Group

3 Citations (Scopus)

Abstract

OBJECTIVES: To evaluate the importance of a history of hypertension on long-term mortality in a large cohort of patients hospitalised with congestive heart failure (CHF). DESIGN: Retrospective analysis of 5491 consecutive patients, of whom 24% had a history of hypertension. 60% of the patients had non-systolic CHF, and 57% had ischaemic heart disease. SETTING: 38 primary, secondary and tertiary hospitals in Denmark. MAIN OUTCOME MEASURES: Total mortality 5-8 years after inclusion in the registry. RESULTS: Female sex and preserved left ventricular systolic function was more common among patients with a history of hypertension. 72% of the patients died during follow up. A hypertension history did not affect mortality risk (hazard ratio (HR) 0.99, 95% confidence interval (CI) 0.92 to 1.07). Correction for differences between the normotensive and hypertensive groups at baseline in a multivariate model did not alter this result (HR 1.08, 95% CI 1.00 to 1.17, p = 0.06). The hazard ratio was similar in patients with and without a history of ischaemic heart disease. Hence, a specific effect of hypertension in the group of patients with CHF with ischaemic heart disease, as suggested in earlier studies, could not be confirmed. CONCLUSION: A history of arterial hypertension did not affect mortality in patients hospitalised with CHF.

Original language	English
Journal	Heart
Volume	92
Issue number	10
Pages (from-to)	1430-3
Number of pages	3
ISSN	1355-6037
DOIs	https://doi.org/10.1136/hrt.2005.080572
Publication status	Published - 2006

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@article{8e205190119b11df803f000ea68e967b,

title = "A history of arterial hypertension does not affect mortality in patients hospitalised with congestive heart failure",

abstract = "OBJECTIVES: To evaluate the importance of a history of hypertension on long-term mortality in a large cohort of patients hospitalised with congestive heart failure (CHF). DESIGN: Retrospective analysis of 5491 consecutive patients, of whom 24% had a history of hypertension. 60% of the patients had non-systolic CHF, and 57% had ischaemic heart disease. SETTING: 38 primary, secondary and tertiary hospitals in Denmark. MAIN OUTCOME MEASURES: Total mortality 5-8 years after inclusion in the registry. RESULTS: Female sex and preserved left ventricular systolic function was more common among patients with a history of hypertension. 72% of the patients died during follow up. A hypertension history did not affect mortality risk (hazard ratio (HR) 0.99, 95% confidence interval (CI) 0.92 to 1.07). Correction for differences between the normotensive and hypertensive groups at baseline in a multivariate model did not alter this result (HR 1.08, 95% CI 1.00 to 1.17, p = 0.06). The hazard ratio was similar in patients with and without a history of ischaemic heart disease. Hence, a specific effect of hypertension in the group of patients with CHF with ischaemic heart disease, as suggested in earlier studies, could not be confirmed. CONCLUSION: A history of arterial hypertension did not affect mortality in patients hospitalised with CHF.",

author = "F Gustafsson and C Torp-Pedersen and M Seibaek and H Burchardt and Nielsen, {O Wendelboe} and L K{\o}ber and {DIAMOND Study Group}",

note = "Keywords: Aged; Aged, 80 and over; Female; Heart Failure; Hospitalization; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Risk Factors; Survival Analysis",

year = "2006",

doi = "10.1136/hrt.2005.080572",

language = "English",

volume = "92",

pages = "1430--3",

journal = "Heart",

issn = "1355-6037",

publisher = "B M J Group",

number = "10",

}

TY - JOUR

T1 - A history of arterial hypertension does not affect mortality in patients hospitalised with congestive heart failure

AU - Gustafsson, F

AU - Torp-Pedersen, C

AU - Seibaek, M

AU - Burchardt, H

AU - Nielsen, O Wendelboe

AU - Køber, L

AU - DIAMOND Study Group

N1 - Keywords: Aged; Aged, 80 and over; Female; Heart Failure; Hospitalization; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Risk Factors; Survival Analysis

PY - 2006

Y1 - 2006

N2 - OBJECTIVES: To evaluate the importance of a history of hypertension on long-term mortality in a large cohort of patients hospitalised with congestive heart failure (CHF). DESIGN: Retrospective analysis of 5491 consecutive patients, of whom 24% had a history of hypertension. 60% of the patients had non-systolic CHF, and 57% had ischaemic heart disease. SETTING: 38 primary, secondary and tertiary hospitals in Denmark. MAIN OUTCOME MEASURES: Total mortality 5-8 years after inclusion in the registry. RESULTS: Female sex and preserved left ventricular systolic function was more common among patients with a history of hypertension. 72% of the patients died during follow up. A hypertension history did not affect mortality risk (hazard ratio (HR) 0.99, 95% confidence interval (CI) 0.92 to 1.07). Correction for differences between the normotensive and hypertensive groups at baseline in a multivariate model did not alter this result (HR 1.08, 95% CI 1.00 to 1.17, p = 0.06). The hazard ratio was similar in patients with and without a history of ischaemic heart disease. Hence, a specific effect of hypertension in the group of patients with CHF with ischaemic heart disease, as suggested in earlier studies, could not be confirmed. CONCLUSION: A history of arterial hypertension did not affect mortality in patients hospitalised with CHF.

AB - OBJECTIVES: To evaluate the importance of a history of hypertension on long-term mortality in a large cohort of patients hospitalised with congestive heart failure (CHF). DESIGN: Retrospective analysis of 5491 consecutive patients, of whom 24% had a history of hypertension. 60% of the patients had non-systolic CHF, and 57% had ischaemic heart disease. SETTING: 38 primary, secondary and tertiary hospitals in Denmark. MAIN OUTCOME MEASURES: Total mortality 5-8 years after inclusion in the registry. RESULTS: Female sex and preserved left ventricular systolic function was more common among patients with a history of hypertension. 72% of the patients died during follow up. A hypertension history did not affect mortality risk (hazard ratio (HR) 0.99, 95% confidence interval (CI) 0.92 to 1.07). Correction for differences between the normotensive and hypertensive groups at baseline in a multivariate model did not alter this result (HR 1.08, 95% CI 1.00 to 1.17, p = 0.06). The hazard ratio was similar in patients with and without a history of ischaemic heart disease. Hence, a specific effect of hypertension in the group of patients with CHF with ischaemic heart disease, as suggested in earlier studies, could not be confirmed. CONCLUSION: A history of arterial hypertension did not affect mortality in patients hospitalised with CHF.

U2 - 10.1136/hrt.2005.080572

DO - 10.1136/hrt.2005.080572

M3 - Journal article

C2 - 16621877

SN - 1355-6037

VL - 92

SP - 1430

EP - 1433

JO - Heart

JF - Heart

IS - 10

ER -

A history of arterial hypertension does not affect mortality in patients hospitalised with congestive heart failure

Abstract

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