3D analysis of facial asymmetry in subjects with juvenile idiopathic arthritis

TY - JOUR

T1 - 3D analysis of facial asymmetry in subjects with juvenile idiopathic arthritis

AU - Demant, Sune

AU - Hermann, Nuno V

AU - Darvann, Tron A

AU - Zak, Marek

AU - Schatz, Helena

AU - Larsen, Per

AU - Kreiborg, Sven

N1 - Paper id:: Rheumatology 2010; doi: 10.1093/rheumatology/keq329

PY - 2011/3/1

Y1 - 2011/3/1

N2 - Objective: To investigate and compare facial asymmetry in subjects with JIA with unilateral, bilateral or no TM joint (TMJ) involvement. Methods: Eighty-one subjects with JIA: 22 with unilateral TMJ involvement (Group 1), 15 with bilateral TMJ involvement (Group 2) and 44 with no TMJ involvement (Group 3). Panoramic X-rays and three-dimensional (3D) photographs (surface scans) were obtained for all subjects. Panoramic X-rays were rated for severity of TMJ involvement. For each individual, a spatially detailed facial asymmetry map was created from the 3D photograph. Mean and variability of asymmetry were calculated for each of the three groups and compared. Results: Distinct patterns of asymmetry were found in Groups 1 and 2. With mean asymmetry values up to 3.5 mm, Group 1 exhibited a significantly greater amount of asymmetry in a broad band along the lower jaw extending from the region of the condyle to the chin than Group 2. The mean facial asymmetry (1 s.d.) for each JIA group was 2.3 (0.9), 2.0 (0.7), 1.7 (0.5) mm for Groups 1, 2 and 3, respectively. Conclusion: JIA subjects with TMJ involvement displayed patterns of facial asymmetry consistent with the destruction of the condylar growth centre, leading to mandibular asymmetry with displacement of the bony chin. Facial asymmetry quantification was found to be an effective method for assessing both the amount and the localization and spatial extent of asymmetry in all 3Ds.

AB - Objective: To investigate and compare facial asymmetry in subjects with JIA with unilateral, bilateral or no TM joint (TMJ) involvement. Methods: Eighty-one subjects with JIA: 22 with unilateral TMJ involvement (Group 1), 15 with bilateral TMJ involvement (Group 2) and 44 with no TMJ involvement (Group 3). Panoramic X-rays and three-dimensional (3D) photographs (surface scans) were obtained for all subjects. Panoramic X-rays were rated for severity of TMJ involvement. For each individual, a spatially detailed facial asymmetry map was created from the 3D photograph. Mean and variability of asymmetry were calculated for each of the three groups and compared. Results: Distinct patterns of asymmetry were found in Groups 1 and 2. With mean asymmetry values up to 3.5 mm, Group 1 exhibited a significantly greater amount of asymmetry in a broad band along the lower jaw extending from the region of the condyle to the chin than Group 2. The mean facial asymmetry (1 s.d.) for each JIA group was 2.3 (0.9), 2.0 (0.7), 1.7 (0.5) mm for Groups 1, 2 and 3, respectively. Conclusion: JIA subjects with TMJ involvement displayed patterns of facial asymmetry consistent with the destruction of the condylar growth centre, leading to mandibular asymmetry with displacement of the bony chin. Facial asymmetry quantification was found to be an effective method for assessing both the amount and the localization and spatial extent of asymmetry in all 3Ds.

U2 - 10.1093/rheumatology/keq329

DO - 10.1093/rheumatology/keq329

M3 - Journal article

C2 - 21097878

SN - 1462-0324

VL - 50

SP - 586

EP - 592

JO - Rheumatology

JF - Rheumatology

IS - 3

ER -