14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins

Alastair Aitken*, D. B. Collinge, B. P.H. van Heusden, T. Isobe, P. H. Roseboom, G. Rosenfeld, J. Soll

*Corresponding author for this work
412 Citations (Scopus)

Abstract

A family of proteins known as 14-3-3 is currently receiving increased attention by investigators studying a broad range of biological systems, including plants and invertebrates. The outstanding feature of this family is the extraordinarily high sequence conservation observed. Current thinking indicates that these proteins may function as regulators in signal tranduction/phosphorylation mechanisms.

Original languageEnglish
JournalTrends in Biochemical Sciences
Volume17
Issue number12
Pages (from-to)498-501
Number of pages4
ISSN0968-0004
DOIs
Publication statusPublished - 1 Jan 1992

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