11.74T fMRI of cortical and subcortical visual networks in the rat

Christopher Bailey; Basavaraju G. Sanganahalli; Alyssa Siefert; Herman Peter; Albert Gjedde; Fahmeed Hyder

11.74T fMRI of cortical and subcortical visual networks in the rat

Christopher Bailey, Basavaraju G. Sanganahalli, Alyssa Siefert, Herman Peter, Albert Gjedde, Fahmeed Hyder

Department of Neuroscience

Abstract

Though a predominantly nocturnal animal, the rat has a functional visual system, albeit of low acuity, and has at least a basic form of color vision extending into the UV range. Our aim here was to develop methods to probe this system with both high field fMRI and electrophysiological techniques. Experimental setups in an imaging spectrometer are not ideally suited for studying the visual pathway of the rodent due to stringent physical constraints imposed by the imaging bore size and strong magnetic field. Here we report a method, applicable to both data acquisition scenarios, for specific and reproducible delivery of visual stimuli in fMRI as well as neurophysiology environments. It has the advantage of allowing variation of the stimulus source (e.g. colour of LED) without the need for manipulating the subject in the bore.

Original language	English
Publication date	2008
Publication status	Published - 2008
Event	16th ISMRM - Toronto, Canada Duration: 3 May 2008 → 9 May 2008

Conference

Conference	16th ISMRM
Country/Territory	Canada
City	Toronto
Period	03/05/2008 → 09/05/2008

Cite this

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AU - Bailey, Christopher

AU - Sanganahalli, Basavaraju G.

AU - Siefert, Alyssa

AU - Peter, Herman

AU - Gjedde, Albert

AU - Hyder, Fahmeed

PY - 2008

Y1 - 2008

N2 - Though a predominantly nocturnal animal, the rat has a functional visual system, albeit of low acuity, and has at least a basic form of color vision extending into the UV range. Our aim here was to develop methods to probe this system with both high field fMRI and electrophysiological techniques. Experimental setups in an imaging spectrometer are not ideally suited for studying the visual pathway of the rodent due to stringent physical constraints imposed by the imaging bore size and strong magnetic field. Here we report a method, applicable to both data acquisition scenarios, for specific and reproducible delivery of visual stimuli in fMRI as well as neurophysiology environments. It has the advantage of allowing variation of the stimulus source (e.g. colour of LED) without the need for manipulating the subject in the bore.

AB - Though a predominantly nocturnal animal, the rat has a functional visual system, albeit of low acuity, and has at least a basic form of color vision extending into the UV range. Our aim here was to develop methods to probe this system with both high field fMRI and electrophysiological techniques. Experimental setups in an imaging spectrometer are not ideally suited for studying the visual pathway of the rodent due to stringent physical constraints imposed by the imaging bore size and strong magnetic field. Here we report a method, applicable to both data acquisition scenarios, for specific and reproducible delivery of visual stimuli in fMRI as well as neurophysiology environments. It has the advantage of allowing variation of the stimulus source (e.g. colour of LED) without the need for manipulating the subject in the bore.

M3 - Poster

T2 - 16th ISMRM

Y2 - 3 May 2008 through 9 May 2008

ER -

11.74T fMRI of cortical and subcortical visual networks in the rat

Abstract

Conference

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