Diego Iglesias Gato

2019

Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer

Flores-Morales, A., Bergmann, T. B., Lavallee, C., Batth, T. S., Lin, D., Lerdrup, M., Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, K., Røder, M. A., Brasso, K., Moreira, J. M., Bjartell, A., Wang, Y., Olsen, J. V., Collins, C. C., & 1 othersIglesias-Gato, D., 15 Jan 2019, In: Clinical Cancer Research. 25, 2, p. 1-15

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

2018

Predictive value of combined analysis of pro-NPY and ERG in localized prostate cancer

Kristensen, G., Røder, M. A., Berg, K. D., Elversang, J., Iglesias-Gato, D., Moreira, J., Toft, B. G. & Brasso, K., Oct 2018, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 126, 10, p. 804-813

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability

Hjorth-Jensen, K., Maya-Mendoza, A., Dalgaard, N., Sigurðsson, J. O., Bartek, J., Iglesias-Gato, D., Olsen, J. V. & Flores-Morales, A., 12 Oct 2018, In: Nucleic Acids Research. 46, 18, p. 9484-9495

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

84 Downloads (Pure)

The proteome of prostate cancer bone metastasis reveals heterogeneity with prognostic implications

Iglesias-Gato, D., Thysell, E., Tyanova, S., Crnalic, S., Santos, A., Lima, T. S., Geiger, T., Cox, J., Widmark, A., Bergh, A., Mann, M., Flores-Morales, A. & Wikström, P., 1 Nov 2018, In: Clinical Cancer Research. 24, 21, p. 5433-5444 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

2017

Quantitative Mass Spectrometry-Based Proteomic Profiling for Precision Medicine in Prostate Cancer

Flores-Morales, A. & Iglesias-Gato, D., 7 Nov 2017, In: Frontiers in Oncology. 7, p. 1-8 00267.

Research output: Contribution to journal › Review › peer-review

12 Citations (Scopus)

69 Downloads (Pure)

The ubiquitin ligase Cullin5^SOCS2 regulates NDR1/STK38 stability and NF-κB transactivation

Paul, I., Batth, T. S., Iglesias-Gato, D., Al-Araimi, A., Al-Haddabi, I., Alkharusi, A., Norstedt, G., Olsen, J. V., Zadjali, F. & Flores-Morales, A., 20 Feb 2017, In: Scientific Reports. 7, 14 p., 42800.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

94 Downloads (Pure)

YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth

Jiang, N., Ke, B., Hjort-Jensen, K., Iglesias-Gato, D., Wang, Z., Chang, P., Zhao, Y., Niu, X., Wu, T., Peng, B., Jiang, M., Li, X., Shang, Z., Wang, Q., Chang, C., Flores-Morales, A. & Niu, Y., 2017, In: OncoTarget. 8, 70, p. 115054-115067 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

161 Downloads (Pure)

2016

Growth Hormone Receptor Signaling Pathways and its Negative Regulation by SOCS2

Fernández Pérez, L., Flores-Morales, A., Guerra, B., Díaz-Chico, J. C. & Iglesias Gato, D., Oct 2016, Restricted Growth: Clinical, Genetic and Molecular Aspects. del Carmen Cardenas- Aguayo, M. (ed.). InTechOpen, p. 125-145 21 p.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

The Proteome of Primary Prostate Cancer

Iglesias-Gato, D., Wikström, P., Tyanova, S., Lavallee, C., Thysell, E., Carlsson, J., Hägglöf, C., Cox, J., Andrén, O., Stattin, P., Egevad, L., Widmark, A., Bjartell, A., Collins, C. C., Bergh, A., Geiger, T., Mann, M. & Flores-Morales, A., 1 May 2016, In: European Urology. 69, 5, p. 942-952 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

65 Citations (Scopus)

2015

In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth

Jiang, N., Hjorth-Jensen, K., Hekmat, O., Iglesias Gato, D., Kruse, T., Wang, C., Wei, W., Ke, B., Yan, B., Niu, Y., Olsen, J. V. & Flores Morales, A., 21 May 2015, In: Oncogene. 34, p. 2764–2776 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

39 Citations (Scopus)

OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo: [Plus] erratum

Iglesias-Gato, D., Chuan, Y-C., Jiang, N., Lavallee, C., Bao, J., Paul, I., Egevad, L., Kessler, B. M., Wikström, P., Niu, Y. & Flores-Morales, A., 27 Jan 2015, In: Molecular Cancer. 14, 14 p., 8.

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

2014

Lipid profiling and transcriptomic analysis reveals a functional interplay between estradiol and growth hormone in liver

Fernández-Pérez, L., Santana-Farré, R., Mirecki-Garrido, M. D., García, I., Guerra, B., Mateo-Diaz, C., Iglesias Gato, D., Díaz-Chico, J. C., Flores Morales, A. & Díaz, M., 9 May 2014, In: P L o S One. 9, 19 p., e96305.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

1860 Downloads (Pure)

Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase

Andresen, C. A., Smedegaard, S., Sylvestersen, K. B., Svensson, C., Iglesias-Gato, D., Cazzamali, G., Nielsen, T. K., Nielsen, M. L. & Flores Morales, A., 24 Jan 2014, In: The Journal of Biological Chemistry. 289, 4, p. 2043-2054 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer

Svensson, C., Ceder, J., Iglesias Gato, D., Chuan, Y. C., Pang, S. T., Bjartell, A., Martinez, R. M., Bott, L., Helczynski, L., Ulmert, D., Wang, Y., Niu, Y., Collins, C. & Flores Morales, A., 1 Jan 2014, In: Nucleic Acids Research. 42, 2, p. 999-1015 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

79 Citations (Scopus)

SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer

Iglesias Gato, D., Chuan, Y. C., Wikström, P., Augsten, S., Jiang, N., Niu, Y., Seipel, A., Danneman, D., Vermeij, M., Fernandez-Perez, L., Jenster, G., Egevad, L., Norstedt, G. & Flores Morales, A., Jan 2014, In: Carcinogenesis. 35, 1, p. 24-33

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

2012

Androgen-independent effects of Serenoa repens extract (Prostasan®) on prostatic epithelial cell proliferation and inflammation

Iglesias-Gato, D., Carsten, T., Vesterlund, M., Pousette, A., Schoop, R. & Norstedt, G., Feb 2012, In: Phytotherapy Research. 26, 2, p. 259-64 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

2011

Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN₄ translational control in Saccharomyces cerevisiae

Iglesias Gato, D., Martín-Marcos, P., Santos, M. A., Hinnebusch, A. G. & Tamame, M., Jan 2011, In: Genetics. 187, 1, p. 105-122 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells

Iglesias Gato, D., Zheng, S., Flanagan, J. N., Jiang, L., Kittaka, A., Sakaki, T., Yamamoto, K., Itoh, T., Lebrasseur, N. K., Norstedt, G. & Chen, T. C., Nov 2011, In: Journal of Steroid Biochemistry and Molecular Biology. 127, 3-5, p. 269-75 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

2010

Ezrin mediates c-Myc actions in prostate cancer cell invasion

Chuan, Y. C., Iglesias Gato, D., Fernandez-Perez, L., Cedazo-Minguez, A., Pang, S-T., Norstedt, G., Pousette, A. & Flores-Morales, A., Mar 2010, In: Oncogene. 29, 10, p. 1531-42 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

47 Citations (Scopus)

2009

Anti-proliferative effects by Sabal serrulata (Prostasan (R)) on prostatic cell lines

Iglesias Gato, D., Pousette, A., Flores Morales, A., Norstedt, G. & Schoop, R., Jul 2009, In: Planta Medica. 75, 9, p. 985-985

Research output: Contribution to journal › Journal article › Research

Diego Iglesias Gato

Research output

Search results