Identification and validation of 174 COVID‑19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

  • Marek Prachar (Creator)
  • Sune Justesen (Creator)
  • Daniel Bisgaard Steen-Jensen (Immunitrack ApS, Copenhagen, Denmark) (Creator)
  • Stephan Thorgrimsen (Creator)
  • Erik Jurgons (Creator)
  • Ole Winther (Creator)
  • Frederik Otzen Bagger (Creator)

Dataset

Description

Datasets used in "Identification and validation of 174 COVID‑19 vaccine candidate epitopes reveals low performance of common epitope prediction tools" sars-cov-2_predicted.csv SARS-CoV-2 peptides predicted to be binders to 11 HLA alleles by the NetMHC suite tools, these selected peptides have been measured in a stability assay revealing SARS-CoV-2 epitopes (assay results can be found at: https://www.immunitrack.com/free-coronavirus-report-for-download/). tools_predictions_binders.xlsx File containing all predictions for tools tested in the benchmark (note that not all tools use same measure). List of binders (epitopes) with IEDB links and T cell studies overlap.
Date made available2020
PublisherZenodo

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