TY - JOUR
T1 - Vitamin d status in patients with chronic obstructive pulmonary disease who participate in pulmonary rehabilitation
AU - Ringbaek, Thomas
AU - Martinez, Gerd
AU - Durakovic, Amal
AU - Thøgersen, Jane
AU - Midjord, Anne-Kirsten
AU - Jensen, Jens-Erik Beck
AU - Lange, Peter
PY - 2011/7
Y1 - 2011/7
N2 - Purpose: Vitamin D deficiency is common in patients with chronic obstructive pulmonary disease; however, no study has evaluated the influence of vitamin D status on effects of pulmonary rehabilitation (PR). Methods: We studied 311 patients, who participated in a 7-week outpatient PR. Vitamin D status was assessed at entry and examined for association with patient characteristics, dropout from PR, and effect on endurance shuttle walk time. Results: Vitamin D level < 25 nM was seen in 61 (19.6%) of the patients. They were significantly younger, were more frequently on long-term oxygen therapy, had higher body mass index and fat-free mass index, had worse quality of life score, tended to have lower percent predicted value for forced expiratory volume in the first second of expiration, and more frequently were current smokers. They had a 3-time higher risk of dropout from the PR program (P = .003) compared with patients with normal vitamin D status and a poorer improvement in endurance shuttle walk time (P = .03). DISCUSSION:: In conclusion, vitamin D deficiency was significantly associated with higher dropout rates from PR, and there was a tendency toward a poorer improvement in endurance shuttle walk time.
AB - Purpose: Vitamin D deficiency is common in patients with chronic obstructive pulmonary disease; however, no study has evaluated the influence of vitamin D status on effects of pulmonary rehabilitation (PR). Methods: We studied 311 patients, who participated in a 7-week outpatient PR. Vitamin D status was assessed at entry and examined for association with patient characteristics, dropout from PR, and effect on endurance shuttle walk time. Results: Vitamin D level < 25 nM was seen in 61 (19.6%) of the patients. They were significantly younger, were more frequently on long-term oxygen therapy, had higher body mass index and fat-free mass index, had worse quality of life score, tended to have lower percent predicted value for forced expiratory volume in the first second of expiration, and more frequently were current smokers. They had a 3-time higher risk of dropout from the PR program (P = .003) compared with patients with normal vitamin D status and a poorer improvement in endurance shuttle walk time (P = .03). DISCUSSION:: In conclusion, vitamin D deficiency was significantly associated with higher dropout rates from PR, and there was a tendency toward a poorer improvement in endurance shuttle walk time.
KW - Aged
KW - Confidence Intervals
KW - Exercise Test
KW - Female
KW - Forced Expiratory Volume
KW - Health Status Indicators
KW - Health Surveys
KW - Humans
KW - Linear Models
KW - Logistic Models
KW - Male
KW - Odds Ratio
KW - Outpatients
KW - Patient Participation
KW - Pulmonary Disease, Chronic Obstructive
KW - Statistics as Topic
KW - Statistics, Nonparametric
KW - Surveys and Questionnaires
KW - Vital Capacity
KW - Vitamin D
KW - Vitamin D Deficiency
U2 - 10.1097/hcr.0b013e31821c13aa
DO - 10.1097/hcr.0b013e31821c13aa
M3 - Journal article
C2 - 21623214
SN - 1932-7501
VL - 31
SP - 261
EP - 267
JO - Journal of Cardiopulmonary Rehabilitation and Prevention
JF - Journal of Cardiopulmonary Rehabilitation and Prevention
IS - 4
ER -