Visualizing biofilm by targeting eDNA with long wavelength probe CDr15

Haw Young Kwon, Jun Young Kim, Xiao Liu, Jung Yeol Lee, Joey Kuok Hoong Yam, Louise Dahl Hultqvist, Wang Xu, Morten Rybtke, Tim Tolker-Nielsen, Wooseok Heo, Jong Jin Kim, Nam Young Kang, Taiha Joo, Liang Yang, Sung Jin Park*, Michael Givskov, Young Tae Chang

*Corresponding author af dette arbejde
    1 Citationer (Scopus)

    Abstract

    Detection of the biofilm of bacteria would be a counter strategy to detect hidden bacteria in their camouflage. Through unbiased screening of bacteria biofilm, we discovered a long wavelength probe CDr15 with extracellular DNA as the molecular target. CDr15 revealed a real-time geometric distribution of eDNA in a 3D bacterial colony.

    OriginalsprogEngelsk
    TidsskriftBiomaterials Science
    Vol/bind7
    Udgave nummer9
    Sider (fra-til)3594-3598
    Antal sider5
    ISSN2047-4830
    DOI
    StatusUdgivet - 2019

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