TY - JOUR
T1 - Validation of non-invasive haemodynamic methods in patients with liver disease
T2 - the Finometer and the Task Force Monitor
AU - Brittain, Jane M.
AU - Busk, Troels M.
AU - Møller, Søren
PY - 2018
Y1 - 2018
N2 - Patients with advanced cirrhosis often present a hyperdynamic circulation characterized by a decrease in systolic and diastolic blood pressure (SBP and DBP), and an increase in heart rate (HR) and cardiac output (CO). Accurate assessment of the altered circulation can be performed invasively; however, due to the disadvantages of this approach, non-invasive methods are warranted. The purpose of this study was to compare continuous non-invasive measurements of haemodynamic variables by the Finometer and the Task Force Monitor with simultaneous invasive measurements. In 25 patients with cirrhosis, SBP, DBP and HR were measured non-invasively and by femoral artery catheterization. CO was measured non-invasively and by indicator dilution technique. The non-invasive pressure monitoring was considered acceptable with a bias (accuracy) and a SD (precision) not exceeding 5 and 8 mmHg, respectively, as recommended by the Association for the Advancement of Medical Instrumentation. The accuracy and precision of the Finometer and the Task Force Monitor were as follows: SBP: −3·6 ± 17·9 and −8·9 ± 17·5 mmHg, respectively; DBP: 4·2 ± 9·6 and 1·9 ± 8·6 mmHg, respectively; HR: 2·0 ± 6·9 and 2·2 ± 6·2 bpm, respectively; and CO: 0·1 ± 1·6 and −1·0 ± 2·0 L min−1, respectively. The study demonstrates that the overall performances of the Finometer and the Task Force Monitor in estimating absolute values of SBP, DBP, HR and CO in patients with cirrhosis are not equivalent to the gold standard, but may have an acceptable performance with repeated measurements.
AB - Patients with advanced cirrhosis often present a hyperdynamic circulation characterized by a decrease in systolic and diastolic blood pressure (SBP and DBP), and an increase in heart rate (HR) and cardiac output (CO). Accurate assessment of the altered circulation can be performed invasively; however, due to the disadvantages of this approach, non-invasive methods are warranted. The purpose of this study was to compare continuous non-invasive measurements of haemodynamic variables by the Finometer and the Task Force Monitor with simultaneous invasive measurements. In 25 patients with cirrhosis, SBP, DBP and HR were measured non-invasively and by femoral artery catheterization. CO was measured non-invasively and by indicator dilution technique. The non-invasive pressure monitoring was considered acceptable with a bias (accuracy) and a SD (precision) not exceeding 5 and 8 mmHg, respectively, as recommended by the Association for the Advancement of Medical Instrumentation. The accuracy and precision of the Finometer and the Task Force Monitor were as follows: SBP: −3·6 ± 17·9 and −8·9 ± 17·5 mmHg, respectively; DBP: 4·2 ± 9·6 and 1·9 ± 8·6 mmHg, respectively; HR: 2·0 ± 6·9 and 2·2 ± 6·2 bpm, respectively; and CO: 0·1 ± 1·6 and −1·0 ± 2·0 L min−1, respectively. The study demonstrates that the overall performances of the Finometer and the Task Force Monitor in estimating absolute values of SBP, DBP, HR and CO in patients with cirrhosis are not equivalent to the gold standard, but may have an acceptable performance with repeated measurements.
KW - blood pressure
KW - blood pressure monitors
KW - cardiac output
KW - cirrhosis
KW - heart rate
KW - indicator dilution technique
KW - peripheral arterial catheterization
KW - radioisotope dilution technique
U2 - 10.1111/cpf.12425
DO - 10.1111/cpf.12425
M3 - Journal article
C2 - 28402021
AN - SCOPUS:85017464307
SN - 1475-0961
VL - 38
SP - 384
EP - 389
JO - Clinical Physiology and Functional Imaging
JF - Clinical Physiology and Functional Imaging
IS - 3
ER -