Use of Probiotics in Future Prevention and Treatment of Oral Infections

TY - CHAP

T1 - Use of Probiotics in Future Prevention and Treatment of Oral Infections

AU - Jørgensen, Mette Rose

AU - Keller, Mette Kirstine

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The interest for probiotic bacteria to combat biofilm-related diseases in the oral cavity has arisen during the last decade. The probiotic concept has successfully been used to control gastrointestinal diseases, such as antibiotic-associated diarrhoea and acute infectious diarrhoea. The potential mechanisms of action in the oral cavity are not fully understood, but there are thoughts to be a local effect in the mouth and systemic effect through immune regulation. The purpose of this chapter is to summarise our current knowledge of the potential for probiotics to improve oral and dental health and to discuss its potential in the future prevention of oral diseases. Despite some limitations, the currently available clinical studies appear expectant, and there seem to be evidence of probiotics to improve oral conditions such as dental caries, periodontitis and the colonisation of Candida. However, more long-term clinical studies are needed before evidence-based guidelines can be released.

AB - The interest for probiotic bacteria to combat biofilm-related diseases in the oral cavity has arisen during the last decade. The probiotic concept has successfully been used to control gastrointestinal diseases, such as antibiotic-associated diarrhoea and acute infectious diarrhoea. The potential mechanisms of action in the oral cavity are not fully understood, but there are thoughts to be a local effect in the mouth and systemic effect through immune regulation. The purpose of this chapter is to summarise our current knowledge of the potential for probiotics to improve oral and dental health and to discuss its potential in the future prevention of oral diseases. Despite some limitations, the currently available clinical studies appear expectant, and there seem to be evidence of probiotics to improve oral conditions such as dental caries, periodontitis and the colonisation of Candida. However, more long-term clinical studies are needed before evidence-based guidelines can be released.

U2 - 10.1007/978-3-319-25091-5_12

DO - 10.1007/978-3-319-25091-5_12

M3 - Book chapter

SN - 978-3-319-25089-2

SP - 125

EP - 136

BT - Oral Infections and General Health

A2 - Pedersen, Anne Marie Lynge

PB - Springer

CY - Heidelberg

ER -