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Two distinct sites in sonic Hedgehog combine for heparan sulfate interactions and cell signaling functions
Shu-Chun Chang, Barbara Mulloy, Anthony I Magee,
John R Couchman
Nutritional Immunology
47
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Alfabetisk
Medicin og biovidenskab
Adenocarcinoma
20%
Alkaline Phosphatase
11%
Biological Assay
13%
Embryonic Development
11%
Gene Expression
7%
Hedgehog Proteins
98%
Heparan Sulfate Proteoglycans
50%
Heparin
35%
heparin proteoglycan
21%
Heparitin Sulfate
95%
Lysine
25%
Mutant Proteins
13%
Mutation
14%
Neoplasms
4%
Normal Distribution
15%
Osteoblasts
12%
Proteins
4%
RNA Interference
12%
Signal Transduction
60%
Syndecan-4
20%
Kemiske forbindelser
Bioactivity
14%
Bioassay
18%
Developmental
23%
Heparan Sulfate
100%
Heparan Sulfate Proteoglycan
88%
Heparin
40%
Lysine
36%
Molecular Modeling
17%
Mutation
32%
Protein
32%