True ovarian volume is underestimated by two-dimensional transvaginal ultrasound measurement

Mikkel Rosendahl, Erik Ernst, Per Emil Rasmussen, Claus Yding Andersen

    31 Citationer (Scopus)

    Abstract

    Objective: To investigate a possible difference between true ovarian volume and ovarian volume estimated with two-dimensional (2D) transvaginal ultrasound. Design: Prospective clinical and laboratory study. Setting: University hospital research laboratory. Patient(s): Premenopausal girls and women from three Danish national fertility centers (A: n = 42; B: n = 6; C: n = 18), who had one entire ovary removed for cryopreservation of ovarian cortex. Intervention(s): Transvaginal 2D ultrasound measurement of ovarian volume before oophorectomy. True ovarian volume was obtained by weighing the ovary. Main Outcome Measure(s): Ovarian volume estimated by weight and ultrasound. Result(s): Ovarian tissue density was 1.00 g/mL. Mean ovarian volume by ultrasound vs. weight in the three groups was as follows: A: 6.3 mL vs. 7.8 mL; B: 5.4 mL vs. 6.8 mL; and C: 2.8 mL vs. 6.1 ml. Ovarian volume obtained by ultrasound was at least 27% smaller than the true ovarian volume. Conclusion(s): Ovarian volume was severely underestimated by transvaginal 2D ultrasound measurement.

    OriginalsprogEngelsk
    TidsskriftFertility and Sterility
    Vol/bind93
    Udgave nummer3
    Sider (fra-til)995-8
    Antal sider4
    ISSN0015-0282
    DOI
    StatusUdgivet - 1 feb. 2010

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