Transposable element islands facilitate adaptation to novel environments in an invasive species

Lukas Schrader; Jay W Kim; Daniel Ence; Aleksey Zimin; Antonia Klein; Katharina Wyschetzki; Tobias Weichselgartner; Carsten Kemena; Johannes Stökl; Eva Schultner; Yannick Wurm; Christopher D Smith; Mark Yandell; Jürgen Heinze; Jürgen Gadau; Jan Oettler

doi:10.1038/ncomms6495

Transposable element islands facilitate adaptation to novel environments in an invasive species

Lukas Schrader, Jay W Kim, Daniel Ence, Aleksey Zimin, Antonia Klein, Katharina Wyschetzki, Tobias Weichselgartner, Carsten Kemena, Johannes Stökl, Eva Schultner, Yannick Wurm, Christopher D Smith, Mark Yandell, Jürgen Heinze, Jürgen Gadau, Jan Oettler

88 Citationer (Scopus)

Abstract

Adaptation requires genetic variation, but founder populations are generally genetically depleted. Here we sequence two populations of an inbred ant that diverge in phenotype to determine how variability is generated. Cardiocondyla obscurior has the smallest of the sequenced ant genomes and its structure suggests a fundamental role of transposable elements (TEs) in adaptive evolution. Accumulations of TEs (TE islands) comprising 7.18% of the genome evolve faster than other regions with regard to single-nucleotide variants, gene/exon duplications and deletions and gene homology. A non-random distribution of gene families, larvae/adult specific gene expression and signs of differential methylation in TE islands indicate intragenomic differences in regulation, evolutionary rates and coalescent effective population size. Our study reveals a tripartite interplay between TEs, life history and adaptation in an invasive species.

Originalsprog	Engelsk
Artikelnummer	5495
Tidsskrift	Nature Communications
Vol/bind	5
Antal sider	10
ISSN	2041-1723
DOI	https://doi.org/10.1038/ncomms6495
Status	Udgivet - dec. 2014
Udgivet eksternt	Ja

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10.1038/ncomms6495

ncomms6495.pdfForlagets udgivne version, 1,36 MBLicens: CC BY

Citationsformater

Schrader, L., Kim, J. W., Ence, D., Zimin, A., Klein, A., Wyschetzki, K., Weichselgartner, T., Kemena, C., Stökl, J., Schultner, E., Wurm, Y., Smith, C. D., Yandell, M., Heinze, J., Gadau, J., & Oettler, J. (2014). Transposable element islands facilitate adaptation to novel environments in an invasive species. Nature Communications, 5, Artikel 5495. https://doi.org/10.1038/ncomms6495

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abstract = "Adaptation requires genetic variation, but founder populations are generally genetically depleted. Here we sequence two populations of an inbred ant that diverge in phenotype to determine how variability is generated. Cardiocondyla obscurior has the smallest of the sequenced ant genomes and its structure suggests a fundamental role of transposable elements (TEs) in adaptive evolution. Accumulations of TEs (TE islands) comprising 7.18% of the genome evolve faster than other regions with regard to single-nucleotide variants, gene/exon duplications and deletions and gene homology. A non-random distribution of gene families, larvae/adult specific gene expression and signs of differential methylation in TE islands indicate intragenomic differences in regulation, evolutionary rates and coalescent effective population size. Our study reveals a tripartite interplay between TEs, life history and adaptation in an invasive species.",

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doi = "10.1038/ncomms6495",

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volume = "5",

journal = "Nature Communications",

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AU - Schrader, Lukas

AU - Kim, Jay W

AU - Ence, Daniel

AU - Zimin, Aleksey

AU - Klein, Antonia

AU - Wyschetzki, Katharina

AU - Weichselgartner, Tobias

AU - Kemena, Carsten

AU - Stökl, Johannes

AU - Schultner, Eva

AU - Wurm, Yannick

AU - Smith, Christopher D

AU - Yandell, Mark

AU - Heinze, Jürgen

AU - Gadau, Jürgen

AU - Oettler, Jan

PY - 2014/12

Y1 - 2014/12

N2 - Adaptation requires genetic variation, but founder populations are generally genetically depleted. Here we sequence two populations of an inbred ant that diverge in phenotype to determine how variability is generated. Cardiocondyla obscurior has the smallest of the sequenced ant genomes and its structure suggests a fundamental role of transposable elements (TEs) in adaptive evolution. Accumulations of TEs (TE islands) comprising 7.18% of the genome evolve faster than other regions with regard to single-nucleotide variants, gene/exon duplications and deletions and gene homology. A non-random distribution of gene families, larvae/adult specific gene expression and signs of differential methylation in TE islands indicate intragenomic differences in regulation, evolutionary rates and coalescent effective population size. Our study reveals a tripartite interplay between TEs, life history and adaptation in an invasive species.

AB - Adaptation requires genetic variation, but founder populations are generally genetically depleted. Here we sequence two populations of an inbred ant that diverge in phenotype to determine how variability is generated. Cardiocondyla obscurior has the smallest of the sequenced ant genomes and its structure suggests a fundamental role of transposable elements (TEs) in adaptive evolution. Accumulations of TEs (TE islands) comprising 7.18% of the genome evolve faster than other regions with regard to single-nucleotide variants, gene/exon duplications and deletions and gene homology. A non-random distribution of gene families, larvae/adult specific gene expression and signs of differential methylation in TE islands indicate intragenomic differences in regulation, evolutionary rates and coalescent effective population size. Our study reveals a tripartite interplay between TEs, life history and adaptation in an invasive species.

KW - Adaptation, Physiological

KW - Animals

KW - Ants

KW - Biological Evolution

KW - Brazil

KW - DNA Methylation

KW - DNA Transposable Elements

KW - Exons

KW - Gene Deletion

KW - Gene Duplication

KW - Genes, Insect

KW - Genome, Insect

KW - Genomic Islands

KW - Introduced Species

KW - Japan

KW - Phylogeography

KW - Polymorphism, Single Nucleotide

U2 - 10.1038/ncomms6495

DO - 10.1038/ncomms6495

M3 - Journal article

C2 - 25510865

SN - 2041-1723

VL - 5

JO - Nature Communications

JF - Nature Communications

M1 - 5495

ER -

Transposable element islands facilitate adaptation to novel environments in an invasive species

Abstract

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