Transfusion-related mortality after primary hip arthroplasty - an analysis of mechanisms and confounders

TY - JOUR

T1 - Transfusion-related mortality after primary hip arthroplasty - an analysis of mechanisms and confounders

AU - Jans, O

AU - Kehlet, H

AU - Johansson, P I

N1 - © 2012 The Author(s). Vox Sanguinis © 2012 International Society of Blood Transfusion.

PY - 2012/11

Y1 - 2012/11

N2 - Background and Objectives Bleeding and postoperative anaemia after total hip arthroplasty (THA) may trigger transfusion of red blood cells (RBC). However, large observational studies have reported associations between RBC transfusion and increased postoperative morbidity and mortality. As major bleeding or severe postoperative anaemia is intrinsically linked with RBC transfusion, direct causality between transfusion and adverse outcomes remains unclear. This study aimed to identify possible relations between RBC transfusion, severe bleeding or anaemia and mortality in all patients who died

AB - Background and Objectives Bleeding and postoperative anaemia after total hip arthroplasty (THA) may trigger transfusion of red blood cells (RBC). However, large observational studies have reported associations between RBC transfusion and increased postoperative morbidity and mortality. As major bleeding or severe postoperative anaemia is intrinsically linked with RBC transfusion, direct causality between transfusion and adverse outcomes remains unclear. This study aimed to identify possible relations between RBC transfusion, severe bleeding or anaemia and mortality in all patients who died

U2 - 10.1111/j.1423-0410.2012.01612.x

DO - 10.1111/j.1423-0410.2012.01612.x

M3 - Journal article

C2 - 22519366

SN - 0042-9007

VL - 103

SP - 301

EP - 308

JO - Vox Sanguinis

JF - Vox Sanguinis

IS - 4

ER -