Tissue reaction and material characteristics of four bone substitutes

S S Jensen; M Aaboe; E M Pinholt; E Hjørting-Hansen; F Melsen; I E Ruyter

Tissue reaction and material characteristics of four bone substitutes

S S Jensen, M Aaboe, E M Pinholt, E Hjørting-Hansen, F Melsen, I E Ruyter

255 Citationer (Scopus)

Abstract

The aim of the present study was to qualitatively and quantitatively compare the tissue reactions around four different bone substitutes used in orthopedic and craniofacial surgery. Cylinders of two bovine bone substitutes (Endobon and Bio-Oss) and two coral-derived bone substitutes (Pro Osteon 500 and Interpore 500 HA/CC) were implanted into 5-mm bur holes in rabbit tibiae. There was no difference in the amount of newly formed bone around the four biomaterials. Interpore 500 HA/CC resorbed completely, whereas the other three biomaterials did not undergo any detectable biodegradation. Bio-Oss was osseointegrated to a higher degree than the other biomaterials. Material characteristics obtained by diffuse reflectance infrared Fourier transform spectrometry analysis and energy-dispersive spectrometry did not explain the differences in biologic behavior.

Originalsprog	Engelsk
Tidsskrift	International Journal of Oral & Maxillofacial Implants
Vol/bind	11
Udgave nummer	1
Sider (fra-til)	55-66
Antal sider	12
ISSN	0882-2786
Status	Udgivet - 1996

Citationsformater

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title = "Tissue reaction and material characteristics of four bone substitutes",

abstract = "The aim of the present study was to qualitatively and quantitatively compare the tissue reactions around four different bone substitutes used in orthopedic and craniofacial surgery. Cylinders of two bovine bone substitutes (Endobon and Bio-Oss) and two coral-derived bone substitutes (Pro Osteon 500 and Interpore 500 HA/CC) were implanted into 5-mm bur holes in rabbit tibiae. There was no difference in the amount of newly formed bone around the four biomaterials. Interpore 500 HA/CC resorbed completely, whereas the other three biomaterials did not undergo any detectable biodegradation. Bio-Oss was osseointegrated to a higher degree than the other biomaterials. Material characteristics obtained by diffuse reflectance infrared Fourier transform spectrometry analysis and energy-dispersive spectrometry did not explain the differences in biologic behavior.",

keywords = "Animals, Biocompatible Materials, Biodegradation, Environmental, Bone Substitutes, Bone and Bones, Cattle, Cnidaria, Durapatite, Electron Probe Microanalysis, Female, Minerals, Osseointegration, Osteogenesis, Rabbits, Spectroscopy, Fourier Transform Infrared, Tibia",

author = "Jensen, {S S} and M Aaboe and Pinholt, {E M} and E Hj{\o}rting-Hansen and F Melsen and Ruyter, {I E}",

year = "1996",

language = "English",

volume = "11",

pages = "55--66",

journal = "International Journal of Oral and Maxillofacial Implants",

issn = "0882-2786",

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TY - JOUR

T1 - Tissue reaction and material characteristics of four bone substitutes

AU - Jensen, S S

AU - Aaboe, M

AU - Pinholt, E M

AU - Hjørting-Hansen, E

AU - Melsen, F

AU - Ruyter, I E

PY - 1996

Y1 - 1996

N2 - The aim of the present study was to qualitatively and quantitatively compare the tissue reactions around four different bone substitutes used in orthopedic and craniofacial surgery. Cylinders of two bovine bone substitutes (Endobon and Bio-Oss) and two coral-derived bone substitutes (Pro Osteon 500 and Interpore 500 HA/CC) were implanted into 5-mm bur holes in rabbit tibiae. There was no difference in the amount of newly formed bone around the four biomaterials. Interpore 500 HA/CC resorbed completely, whereas the other three biomaterials did not undergo any detectable biodegradation. Bio-Oss was osseointegrated to a higher degree than the other biomaterials. Material characteristics obtained by diffuse reflectance infrared Fourier transform spectrometry analysis and energy-dispersive spectrometry did not explain the differences in biologic behavior.

AB - The aim of the present study was to qualitatively and quantitatively compare the tissue reactions around four different bone substitutes used in orthopedic and craniofacial surgery. Cylinders of two bovine bone substitutes (Endobon and Bio-Oss) and two coral-derived bone substitutes (Pro Osteon 500 and Interpore 500 HA/CC) were implanted into 5-mm bur holes in rabbit tibiae. There was no difference in the amount of newly formed bone around the four biomaterials. Interpore 500 HA/CC resorbed completely, whereas the other three biomaterials did not undergo any detectable biodegradation. Bio-Oss was osseointegrated to a higher degree than the other biomaterials. Material characteristics obtained by diffuse reflectance infrared Fourier transform spectrometry analysis and energy-dispersive spectrometry did not explain the differences in biologic behavior.

KW - Animals

KW - Biocompatible Materials

KW - Biodegradation, Environmental

KW - Bone Substitutes

KW - Bone and Bones

KW - Cattle

KW - Cnidaria

KW - Durapatite

KW - Electron Probe Microanalysis

KW - Female

KW - Minerals

KW - Osseointegration

KW - Osteogenesis

KW - Rabbits

KW - Spectroscopy, Fourier Transform Infrared

KW - Tibia

M3 - Journal article

C2 - 8820123

SN - 0882-2786

VL - 11

SP - 55

EP - 66

JO - International Journal of Oral and Maxillofacial Implants

JF - International Journal of Oral and Maxillofacial Implants

IS - 1

ER -

Tissue reaction and material characteristics of four bone substitutes

Abstract

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