The Treatment of Obese Pregnant Women (TOP) study: a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women

Kristina M Renault; Kirsten Nørgaard; Lisbeth Nilas; Emma M Carlsen; Dina Cortes; Ole Pryds; Niels J Secher

doi:10.1016/j.ajog.2013.09.029

The Treatment of Obese Pregnant Women (TOP) study: a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women

Kristina M Renault, Kirsten Nørgaard, Lisbeth Nilas, Emma M Carlsen, Dina Cortes, Ole Pryds, Niels J Secher

138 Citationer (Scopus)

Abstract

OBJECTIVE: The objective of the study was to assess physical activity intervention assessed by a pedometer with or without dietary intervention on gestational weight gain (GWG) in obese pregnant women by comparing with a control group.

STUDY DESIGN: This study was a randomized controlled trial of 425 obese pregnant women comparing 3 groups: (1) PA plus D, physical activity and dietary intervention (n = 142); (2) PA, physical activity intervention (n = 142); and (3) C, a control group receiving standard care (n = 141). All participants routinely in gestational weeks 11-14 had an initial dietary counseling session and were advised to limit GWG to less than 5 kg. Physical activity intervention included encouragement to increase physical activity, aiming at a daily step count of 11,000, monitored by pedometer assessment on 7 consecutive days every 4 weeks. Dietary intervention included follow-up on a hypocaloric Mediterranean-style diet. Instruction was given by a dietician every 2 weeks. The primary outcome measure was GWG, and the secondary outcome measures were complications of pregnancy and delivery and neonatal outcome.

RESULTS: The study was completed by 389 patients (92%). Median values of GWG (ranges) were lower in each of the intervention groups (PA plus D, 8.6 [-9.6 to 34.1] kg, and group PA, 9.4 [-3.4 to 28.2] kg) compared with the control group (10.9 [-4.4 to 28.7] kg [PA+D vs C]; P = .01; PA vs C; P = .042). No significant difference was found between the 2 intervention groups. In a multivariate analysis, physical activity intervention decreased GWG by a mean of 1.38 kg (P = .040). The Institute of Medicine's recommendations for GWG were more frequently followed in the intervention groups.

CONCLUSION: Physical activity intervention assessed by pedometer with or without dietary follow-up reduced GWG compared with controls in obese pregnant women.

Originalsprog	Engelsk
Tidsskrift	American Journal of Obstetrics and Gynecology
Vol/bind	210
Udgave nummer	2
Sider (fra-til)	134.e1-134.e9
ISSN	0002-9378
DOI	https://doi.org/10.1016/j.ajog.2013.09.029
Status	Udgivet - feb. 2014

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10.1016/j.ajog.2013.09.029

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Citationsformater

Renault, K. M., Nørgaard, K., Nilas, L., Carlsen, E. M., Cortes, D., Pryds, O., & Secher, N. J. (2014). The Treatment of Obese Pregnant Women (TOP) study: a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women. American Journal of Obstetrics and Gynecology, 210(2), 134.e1-134.e9. https://doi.org/10.1016/j.ajog.2013.09.029

The Treatment of Obese Pregnant Women (TOP) study : a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women. / Renault, Kristina M; Nørgaard, Kirsten; Nilas, Lisbeth et al.

I: American Journal of Obstetrics and Gynecology, Bind 210, Nr. 2, 02.2014, s. 134.e1-134.e9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Renault, KM, Nørgaard, K, Nilas, L, Carlsen, EM, Cortes, D, Pryds, O & Secher, NJ 2014, 'The Treatment of Obese Pregnant Women (TOP) study: a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women', American Journal of Obstetrics and Gynecology, bind 210, nr. 2, s. 134.e1-134.e9. https://doi.org/10.1016/j.ajog.2013.09.029

Renault KM, Nørgaard K, Nilas L, Carlsen EM, Cortes D, Pryds O et al. The Treatment of Obese Pregnant Women (TOP) study: a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women. American Journal of Obstetrics and Gynecology. 2014 feb.;210(2):134.e1-134.e9. doi: 10.1016/j.ajog.2013.09.029

Renault, Kristina M ; Nørgaard, Kirsten ; Nilas, Lisbeth et al. / The Treatment of Obese Pregnant Women (TOP) study : a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women. I: American Journal of Obstetrics and Gynecology. 2014 ; Bind 210, Nr. 2. s. 134.e1-134.e9.

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abstract = "OBJECTIVE: The objective of the study was to assess physical activity intervention assessed by a pedometer with or without dietary intervention on gestational weight gain (GWG) in obese pregnant women by comparing with a control group.STUDY DESIGN: This study was a randomized controlled trial of 425 obese pregnant women comparing 3 groups: (1) PA plus D, physical activity and dietary intervention (n = 142); (2) PA, physical activity intervention (n = 142); and (3) C, a control group receiving standard care (n = 141). All participants routinely in gestational weeks 11-14 had an initial dietary counseling session and were advised to limit GWG to less than 5 kg. Physical activity intervention included encouragement to increase physical activity, aiming at a daily step count of 11,000, monitored by pedometer assessment on 7 consecutive days every 4 weeks. Dietary intervention included follow-up on a hypocaloric Mediterranean-style diet. Instruction was given by a dietician every 2 weeks. The primary outcome measure was GWG, and the secondary outcome measures were complications of pregnancy and delivery and neonatal outcome.RESULTS: The study was completed by 389 patients (92%). Median values of GWG (ranges) were lower in each of the intervention groups (PA plus D, 8.6 [-9.6 to 34.1] kg, and group PA, 9.4 [-3.4 to 28.2] kg) compared with the control group (10.9 [-4.4 to 28.7] kg [PA+D vs C]; P = .01; PA vs C; P = .042). No significant difference was found between the 2 intervention groups. In a multivariate analysis, physical activity intervention decreased GWG by a mean of 1.38 kg (P = .040). The Institute of Medicine's recommendations for GWG were more frequently followed in the intervention groups.CONCLUSION: Physical activity intervention assessed by pedometer with or without dietary follow-up reduced GWG compared with controls in obese pregnant women.",

keywords = "Actigraphy, Adult, Combined Modality Therapy, Diet, Mediterranean, Energy Intake, Exercise, Female, Humans, Obesity, Pregnancy, Pregnancy Complications",

author = "Renault, {Kristina M} and Kirsten N{\o}rgaard and Lisbeth Nilas and Carlsen, {Emma M} and Dina Cortes and Ole Pryds and Secher, {Niels J}",

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T1 - The Treatment of Obese Pregnant Women (TOP) study

T2 - a randomized controlled trial of the effect of physical activity intervention assessed by pedometer with or without dietary intervention in obese pregnant women

AU - Renault, Kristina M

AU - Nørgaard, Kirsten

AU - Nilas, Lisbeth

AU - Carlsen, Emma M

AU - Cortes, Dina

AU - Pryds, Ole

AU - Secher, Niels J

PY - 2014/2

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N2 - OBJECTIVE: The objective of the study was to assess physical activity intervention assessed by a pedometer with or without dietary intervention on gestational weight gain (GWG) in obese pregnant women by comparing with a control group.STUDY DESIGN: This study was a randomized controlled trial of 425 obese pregnant women comparing 3 groups: (1) PA plus D, physical activity and dietary intervention (n = 142); (2) PA, physical activity intervention (n = 142); and (3) C, a control group receiving standard care (n = 141). All participants routinely in gestational weeks 11-14 had an initial dietary counseling session and were advised to limit GWG to less than 5 kg. Physical activity intervention included encouragement to increase physical activity, aiming at a daily step count of 11,000, monitored by pedometer assessment on 7 consecutive days every 4 weeks. Dietary intervention included follow-up on a hypocaloric Mediterranean-style diet. Instruction was given by a dietician every 2 weeks. The primary outcome measure was GWG, and the secondary outcome measures were complications of pregnancy and delivery and neonatal outcome.RESULTS: The study was completed by 389 patients (92%). Median values of GWG (ranges) were lower in each of the intervention groups (PA plus D, 8.6 [-9.6 to 34.1] kg, and group PA, 9.4 [-3.4 to 28.2] kg) compared with the control group (10.9 [-4.4 to 28.7] kg [PA+D vs C]; P = .01; PA vs C; P = .042). No significant difference was found between the 2 intervention groups. In a multivariate analysis, physical activity intervention decreased GWG by a mean of 1.38 kg (P = .040). The Institute of Medicine's recommendations for GWG were more frequently followed in the intervention groups.CONCLUSION: Physical activity intervention assessed by pedometer with or without dietary follow-up reduced GWG compared with controls in obese pregnant women.

AB - OBJECTIVE: The objective of the study was to assess physical activity intervention assessed by a pedometer with or without dietary intervention on gestational weight gain (GWG) in obese pregnant women by comparing with a control group.STUDY DESIGN: This study was a randomized controlled trial of 425 obese pregnant women comparing 3 groups: (1) PA plus D, physical activity and dietary intervention (n = 142); (2) PA, physical activity intervention (n = 142); and (3) C, a control group receiving standard care (n = 141). All participants routinely in gestational weeks 11-14 had an initial dietary counseling session and were advised to limit GWG to less than 5 kg. Physical activity intervention included encouragement to increase physical activity, aiming at a daily step count of 11,000, monitored by pedometer assessment on 7 consecutive days every 4 weeks. Dietary intervention included follow-up on a hypocaloric Mediterranean-style diet. Instruction was given by a dietician every 2 weeks. The primary outcome measure was GWG, and the secondary outcome measures were complications of pregnancy and delivery and neonatal outcome.RESULTS: The study was completed by 389 patients (92%). Median values of GWG (ranges) were lower in each of the intervention groups (PA plus D, 8.6 [-9.6 to 34.1] kg, and group PA, 9.4 [-3.4 to 28.2] kg) compared with the control group (10.9 [-4.4 to 28.7] kg [PA+D vs C]; P = .01; PA vs C; P = .042). No significant difference was found between the 2 intervention groups. In a multivariate analysis, physical activity intervention decreased GWG by a mean of 1.38 kg (P = .040). The Institute of Medicine's recommendations for GWG were more frequently followed in the intervention groups.CONCLUSION: Physical activity intervention assessed by pedometer with or without dietary follow-up reduced GWG compared with controls in obese pregnant women.

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KW - Adult

KW - Combined Modality Therapy

KW - Diet, Mediterranean

KW - Energy Intake

KW - Exercise

KW - Female

KW - Humans

KW - Obesity

KW - Pregnancy

KW - Pregnancy Complications

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DO - 10.1016/j.ajog.2013.09.029

M3 - Journal article

C2 - 24060449

SN - 0002-9378

VL - 210

SP - 134.e1-134.e9

JO - American Journal of Obstetrics & Gynecology

JF - American Journal of Obstetrics & Gynecology

IS - 2

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