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The synthetic amphipathic peptidomimetic LTX109 is a potent fungicide that disturbs plasma membrane integrity in a sphingolipid dependent manner
Rasmus Kenneth Bojsen, Rasmus Torbensen, Camilla Eggert Larsen, Anders Folkesson,
Birgitte Regenberg
Molecular Integrative Physiology
23
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629
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Biochemistry, Genetics and Molecular Biology
Sphingolipid
100%
Peptidomimetic
100%
Cell Membrane
100%
Lipid
50%
Anabolism
50%
Arginine
50%
Nucleic Acid
25%
Antibacterial Activity
25%
Ceramide
25%
Gene Deletion
25%
Inositol
25%
Tryptophan
25%
Biofilm
25%
Amino Acid
25%
baker's yeast
25%
Immunology and Microbiology
Cell Membrane
100%
Saccharomyces cerevisiae
75%
Biosynthesis
50%
Arginine
50%
Gene Deletion
25%
Biofilm
25%
Amino Acid
25%
Tryptophan
25%
baker's yeast
25%
Antibacterial Activity
25%
Keyphrases
Plasma Membrane Integrity
100%
ORM2
33%
SKN-1
33%
SYTOX Green
33%
Exponentially Growing Populations
33%
Nucleic Acid Stain
33%