The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro

Medicin og biovidenskab

• Analysis of Variance 3%
• Animals 2%
• Baths 4%
• Capsaicin 10%
• capsazepine 13%
• Cations 4%
• Confocal Microscopy 4%
• Electrodes 3%
• Gravitation 5%
• In Vitro Techniques 25%
• Inhibitory Concentration 50 3%
• Irritants 5%
• Lidocaine 60%
• Local Anesthetics 4%
• Nociceptors 5%
• Oocytes 4%
• Perfusion 3%
• Pharmaceutical Preparations 1%
• QX-314 100%
• Students 3%
• TRPV Cation Channels 79%
• TRPV1 receptor 77%
• Xenopus laevis 5%