The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries

Florence J Dalgard; Uwe Gieler; Lucia Tomas-Aragones; Lars Lien; Francoise Poot; Gregor B E Jemec; Laurent Misery; Csanad Szabo; Dennis Linder; Francesca Sampogna; Andrea W M Evers; Jon Anders Halvorsen; Flora Balieva; Jacek Szepietowski; Dmitry Romanov; Servando E Marron; Ilknur K Altunay; Andrew Y Finlay; Sam S Salek; Jörg Kupfer

doi:10.1038/jid.2014.530

The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries

Florence J Dalgard, Uwe Gieler, Lucia Tomas-Aragones, Lars Lien, Francoise Poot, Gregor B E Jemec, Laurent Misery, Csanad Szabo, Dennis Linder, Francesca Sampogna, Andrea W M Evers, Jon Anders Halvorsen, Flora Balieva, Jacek Szepietowski, Dmitry Romanov, Servando E Marron, Ilknur K Altunay, Andrew Y Finlay, Sam S Salek, Jörg Kupfer

Institut for Klinisk Medicin

350 Citationer (Scopus)

Abstract

The contribution of psychological disorders to the burden of skin disease has been poorly explored, and this is a large-scale study to ascertain the association between depression, anxiety, and suicidal ideation with various dermatological diagnoses. This international multicenter observational cross-sectional study was conducted in 13 European countries. In each dermatology clinic, 250 consecutive adult out-patients were recruited to complete a questionnaire, reporting socio-demographic information, negative life events, and suicidal ideation; depression and anxiety were assessed with the Hospital Anxiety and Depression Scale. A clinical examination was performed. A control group was recruited among hospital employees. There were 4,994 participants--3,635 patients and 1,359 controls. Clinical depression was present in 10.1% patients (controls 4.3%, odds ratio (OR) 2.40 (1.67-3.47)). Clinical anxiety was present in 17.2% (controls 11.1%, OR 2.18 (1.68-2.82)). Suicidal ideation was reported by 12.7% of all patients (controls 8.3%, OR 1.94 (1.33-2.82)). For individual diagnoses, only patients with psoriasis had significant association with suicidal ideation. The association with depression and anxiety was highest for patients with psoriasis, atopic dermatitis, hand eczema, and leg ulcers. These results identify a major additional burden of skin disease and have important clinical implications.

Originalsprog	Engelsk
Tidsskrift	Journal of Investigative Dermatology
Vol/bind	135
Udgave nummer	4
Sider (fra-til)	984-91
Antal sider	8
ISSN	0022-202X
DOI	https://doi.org/10.1038/jid.2014.530
Status	Udgivet - 20 apr. 2015

FN’s Verdensmål

Dette resultat bidrager til følgende verdensmål

Adgang til dokumentet

10.1038/jid.2014.530

Citationsformater

Dalgard, F. J., Gieler, U., Tomas-Aragones, L., Lien, L., Poot, F., Jemec, G. B. E., Misery, L., Szabo, C., Linder, D., Sampogna, F., Evers, A. W. M., Halvorsen, J. A., Balieva, F., Szepietowski, J., Romanov, D., Marron, S. E., Altunay, I. K., Finlay, A. Y., Salek, S. S., & Kupfer, J. (2015). The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries. Journal of Investigative Dermatology, 135(4), 984-91. https://doi.org/10.1038/jid.2014.530

The Psychological Burden of Skin Diseases : A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries. / Dalgard, Florence J; Gieler, Uwe; Tomas-Aragones, Lucia et al.

I: Journal of Investigative Dermatology, Bind 135, Nr. 4, 20.04.2015, s. 984-91.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Dalgard, FJ, Gieler, U, Tomas-Aragones, L, Lien, L, Poot, F, Jemec, GBE, Misery, L, Szabo, C, Linder, D, Sampogna, F, Evers, AWM, Halvorsen, JA, Balieva, F, Szepietowski, J, Romanov, D, Marron, SE, Altunay, IK, Finlay, AY, Salek, SS & Kupfer, J 2015, 'The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries', Journal of Investigative Dermatology, bind 135, nr. 4, s. 984-91. https://doi.org/10.1038/jid.2014.530

@article{20342c78eebe4bc288cac2b5d88e3f3b,

title = "The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries",

abstract = "The contribution of psychological disorders to the burden of skin disease has been poorly explored, and this is a large-scale study to ascertain the association between depression, anxiety, and suicidal ideation with various dermatological diagnoses. This international multicenter observational cross-sectional study was conducted in 13 European countries. In each dermatology clinic, 250 consecutive adult out-patients were recruited to complete a questionnaire, reporting socio-demographic information, negative life events, and suicidal ideation; depression and anxiety were assessed with the Hospital Anxiety and Depression Scale. A clinical examination was performed. A control group was recruited among hospital employees. There were 4,994 participants--3,635 patients and 1,359 controls. Clinical depression was present in 10.1% patients (controls 4.3%, odds ratio (OR) 2.40 (1.67-3.47)). Clinical anxiety was present in 17.2% (controls 11.1%, OR 2.18 (1.68-2.82)). Suicidal ideation was reported by 12.7% of all patients (controls 8.3%, OR 1.94 (1.33-2.82)). For individual diagnoses, only patients with psoriasis had significant association with suicidal ideation. The association with depression and anxiety was highest for patients with psoriasis, atopic dermatitis, hand eczema, and leg ulcers. These results identify a major additional burden of skin disease and have important clinical implications.",

keywords = "Adult, Aged, Anxiety, Cross-Sectional Studies, Depression, Dermatology, Europe, Female, Humans, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Outpatients, Prevalence, Regression Analysis, Skin Diseases, Suicidal Ideation, Surveys and Questionnaires",

author = "Dalgard, {Florence J} and Uwe Gieler and Lucia Tomas-Aragones and Lars Lien and Francoise Poot and Jemec, {Gregor B E} and Laurent Misery and Csanad Szabo and Dennis Linder and Francesca Sampogna and Evers, {Andrea W M} and Halvorsen, {Jon Anders} and Flora Balieva and Jacek Szepietowski and Dmitry Romanov and Marron, {Servando E} and Altunay, {Ilknur K} and Finlay, {Andrew Y} and Salek, {Sam S} and J{\"o}rg Kupfer",

year = "2015",

month = apr,

day = "20",

doi = "10.1038/jid.2014.530",

language = "English",

volume = "135",

pages = "984--91",

journal = "Journal of Investigative Dermatology",

issn = "0022-202X",

publisher = "nature publishing group",

number = "4",

}

TY - JOUR

T1 - The Psychological Burden of Skin Diseases

T2 - A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries

AU - Dalgard, Florence J

AU - Gieler, Uwe

AU - Tomas-Aragones, Lucia

AU - Lien, Lars

AU - Poot, Francoise

AU - Jemec, Gregor B E

AU - Misery, Laurent

AU - Szabo, Csanad

AU - Linder, Dennis

AU - Sampogna, Francesca

AU - Evers, Andrea W M

AU - Halvorsen, Jon Anders

AU - Balieva, Flora

AU - Szepietowski, Jacek

AU - Romanov, Dmitry

AU - Marron, Servando E

AU - Altunay, Ilknur K

AU - Finlay, Andrew Y

AU - Salek, Sam S

AU - Kupfer, Jörg

PY - 2015/4/20

Y1 - 2015/4/20

N2 - The contribution of psychological disorders to the burden of skin disease has been poorly explored, and this is a large-scale study to ascertain the association between depression, anxiety, and suicidal ideation with various dermatological diagnoses. This international multicenter observational cross-sectional study was conducted in 13 European countries. In each dermatology clinic, 250 consecutive adult out-patients were recruited to complete a questionnaire, reporting socio-demographic information, negative life events, and suicidal ideation; depression and anxiety were assessed with the Hospital Anxiety and Depression Scale. A clinical examination was performed. A control group was recruited among hospital employees. There were 4,994 participants--3,635 patients and 1,359 controls. Clinical depression was present in 10.1% patients (controls 4.3%, odds ratio (OR) 2.40 (1.67-3.47)). Clinical anxiety was present in 17.2% (controls 11.1%, OR 2.18 (1.68-2.82)). Suicidal ideation was reported by 12.7% of all patients (controls 8.3%, OR 1.94 (1.33-2.82)). For individual diagnoses, only patients with psoriasis had significant association with suicidal ideation. The association with depression and anxiety was highest for patients with psoriasis, atopic dermatitis, hand eczema, and leg ulcers. These results identify a major additional burden of skin disease and have important clinical implications.

AB - The contribution of psychological disorders to the burden of skin disease has been poorly explored, and this is a large-scale study to ascertain the association between depression, anxiety, and suicidal ideation with various dermatological diagnoses. This international multicenter observational cross-sectional study was conducted in 13 European countries. In each dermatology clinic, 250 consecutive adult out-patients were recruited to complete a questionnaire, reporting socio-demographic information, negative life events, and suicidal ideation; depression and anxiety were assessed with the Hospital Anxiety and Depression Scale. A clinical examination was performed. A control group was recruited among hospital employees. There were 4,994 participants--3,635 patients and 1,359 controls. Clinical depression was present in 10.1% patients (controls 4.3%, odds ratio (OR) 2.40 (1.67-3.47)). Clinical anxiety was present in 17.2% (controls 11.1%, OR 2.18 (1.68-2.82)). Suicidal ideation was reported by 12.7% of all patients (controls 8.3%, OR 1.94 (1.33-2.82)). For individual diagnoses, only patients with psoriasis had significant association with suicidal ideation. The association with depression and anxiety was highest for patients with psoriasis, atopic dermatitis, hand eczema, and leg ulcers. These results identify a major additional burden of skin disease and have important clinical implications.

KW - Adult

KW - Aged

KW - Anxiety

KW - Cross-Sectional Studies

KW - Depression

KW - Dermatology

KW - Europe

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Multivariate Analysis

KW - Odds Ratio

KW - Outpatients

KW - Prevalence

KW - Regression Analysis

KW - Skin Diseases

KW - Suicidal Ideation

KW - Surveys and Questionnaires

U2 - 10.1038/jid.2014.530

DO - 10.1038/jid.2014.530

M3 - Journal article

C2 - 25521458

SN - 0022-202X

VL - 135

SP - 984

EP - 991

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

IS - 4

ER -

The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study among Dermatological Out-Patients in 13 European Countries

Abstract

FN’s Verdensmål

Adgang til dokumentet

Fingeraftryk

Citationsformater