The myosin chaperone UNC45B is involved in lens development and autosomal dominant juvenile cataract

Medicin og biovidenskab

• Alleles 10%
• Amino Acids 10%
• Autosomal Dominant Cataract 100%
• Cataract 26%
• Chromosomes, Human, Pair 17 18%
• Complementary DNA 11%
• Crystalline Lens 18%
• Developmental Genes 19%
• Embryonic Structures 47%
• Eye 17%
• Genome 9%
• High-Throughput Nucleotide Sequencing 13%
• HSP90 Heat-Shock Proteins 18%
• human UNC45B protein 37%
• Injections 16%
• Lenses 54%
• Missense Mutation 14%
• Muscles 8%
• Mutation 8%
• Myocardium 11%
• Myosins 62%
• Nonsense Codon 16%
• Phenotype 8%
• Proteins 10%
• RNA 9%
• Skeletal Muscle 11%
• Yeasts 11%
• Zebrafish 29%