The microbiome of New World vultures

Michael Roggenbuck; Ida Bærholm Schnell; Nikolaj Blom; Jacob Bælum; Mads Frost Bertelsen; Thomas Sicheritz-Pontén; Søren Johannes Sørensen; M. Thomas P. Gilbert; Gary R.  Graves; Lars H.  Hansen

doi:10.1038/ncomms6498

The microbiome of New World vultures

Michael Roggenbuck, Ida Bærholm Schnell, Nikolaj Blom, Jacob Bælum, Mads Frost Bertelsen, Thomas Sicheritz-Pontén, Søren Johannes Sørensen, M. Thomas P. Gilbert, Gary R. Graves, Lars H. Hansen

Microbiology

146 Citationer (Scopus)

Abstract

Vultures are scavengers that fill a key ecosystem niche, in which they have evolved a remarkable tolerance to bacterial toxins in decaying meat. Here we report the first deep metagenomic analysis of the vulture microbiome. Through face and gut comparisons of 50 vultures representing two species, we demonstrate a remarkably conserved low diversity of gut microbial flora. The gut samples contained an average of 76 operational taxonomic units (OTUs) per specimen, compared with 528 OTUs on the facial skin. Clostridia and Fusobacteria, widely pathogenic to other vertebrates, dominate the vulture’s gut microbiota. We reveal a likely faecal–oral–gut route for their origin. DNA of prey species detectable on facial swabs was completely degraded in the gut samples from most vultures, suggesting that the gastrointestinal tracts of vultures are extremely selective. Our findings show a strong adaption of vultures and their bacteria to their food source, exemplifying a specialized host–microbial alliance.

Originalsprog	Engelsk
Artikelnummer	5498
Tidsskrift	Nature Communications
Vol/bind	5
Antal sider	7
ISSN	2041-1723
DOI	https://doi.org/10.1038/ncomms6498
Status	Udgivet - 2014

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10.1038/ncomms6498

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Citationsformater

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AU - Roggenbuck, Michael

AU - Schnell, Ida Bærholm

AU - Blom, Nikolaj

AU - Bælum, Jacob

AU - Bertelsen, Mads Frost

AU - Sicheritz-Pontén, Thomas

AU - Sørensen, Søren Johannes

AU - Gilbert, M. Thomas P.

AU - Graves, Gary R.

AU - Hansen, Lars H.

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N2 - Vultures are scavengers that fill a key ecosystem niche, in which they have evolved a remarkable tolerance to bacterial toxins in decaying meat. Here we report the first deep metagenomic analysis of the vulture microbiome. Through face and gut comparisons of 50 vultures representing two species, we demonstrate a remarkably conserved low diversity of gut microbial flora. The gut samples contained an average of 76 operational taxonomic units (OTUs) per specimen, compared with 528 OTUs on the facial skin. Clostridia and Fusobacteria, widely pathogenic to other vertebrates, dominate the vulture’s gut microbiota. We reveal a likely faecal–oral–gut route for their origin. DNA of prey species detectable on facial swabs was completely degraded in the gut samples from most vultures, suggesting that the gastrointestinal tracts of vultures are extremely selective. Our findings show a strong adaption of vultures and their bacteria to their food source, exemplifying a specialized host–microbial alliance.

AB - Vultures are scavengers that fill a key ecosystem niche, in which they have evolved a remarkable tolerance to bacterial toxins in decaying meat. Here we report the first deep metagenomic analysis of the vulture microbiome. Through face and gut comparisons of 50 vultures representing two species, we demonstrate a remarkably conserved low diversity of gut microbial flora. The gut samples contained an average of 76 operational taxonomic units (OTUs) per specimen, compared with 528 OTUs on the facial skin. Clostridia and Fusobacteria, widely pathogenic to other vertebrates, dominate the vulture’s gut microbiota. We reveal a likely faecal–oral–gut route for their origin. DNA of prey species detectable on facial swabs was completely degraded in the gut samples from most vultures, suggesting that the gastrointestinal tracts of vultures are extremely selective. Our findings show a strong adaption of vultures and their bacteria to their food source, exemplifying a specialized host–microbial alliance.

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The microbiome of New World vultures

Abstract

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