TY - JOUR
T1 - The Intracranial Distribution of Gliomas in Relation to Exposure From Mobile Phones
T2 - Analyses From the INTERPHONE Study
AU - Grell, Kathrine
AU - Frederiksen, Kirsten
AU - Schüz, Joachim
AU - Cardis, Elisabeth
AU - Armstrong, Bruce
AU - Siemiatycki, Jack
AU - Krewski, Daniel R
AU - McBride, Mary L
AU - Johansen, Christoffer
AU - Auvinen, Anssi
AU - Hours, Martine
AU - Blettner, Maria
AU - Sadetzki, Siegal
AU - Lagorio, Susanna
AU - Yamaguchi, Naohito
AU - Woodward, Alistair
AU - Tynes, Tore
AU - Feychting, Maria
AU - Fleming, Sarah J
AU - Swerdlow, Anthony J
AU - Andersen, Per K
N1 - © The Author 2016. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: [email protected].
PY - 2016/12/1
Y1 - 2016/12/1
N2 - When investigating the association between brain tumors and use of mobile telephones, accurate data on tumor position are essential, due to the highly localized absorption of energy in the human brain from the radiofrequency fields emitted. We used a point process model to investigate this association using information that included tumor localization data from the INTERPHONE Study (Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden, and the United Kingdom). Our main analysis included 792 regular mobile phone users diagnosed with a glioma between 2000 and 2004. Similar to earlier results, we found a statistically significant association between the intracranial distribution of gliomas and the selfreported location of the phone. When we accounted for the preferred side of the head not being exclusively used for all mobile phone calls, the results were similar. The association was independent of the cumulative call time and cumulative number of calls. However, our model used reported side of mobile phone use, which is potentially influenced by recall bias. The point process method provides an alternative to previously used epidemiologic research designs when one is including localization in the investigation of brain tumors and mobile phone use.
AB - When investigating the association between brain tumors and use of mobile telephones, accurate data on tumor position are essential, due to the highly localized absorption of energy in the human brain from the radiofrequency fields emitted. We used a point process model to investigate this association using information that included tumor localization data from the INTERPHONE Study (Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden, and the United Kingdom). Our main analysis included 792 regular mobile phone users diagnosed with a glioma between 2000 and 2004. Similar to earlier results, we found a statistically significant association between the intracranial distribution of gliomas and the selfreported location of the phone. When we accounted for the preferred side of the head not being exclusively used for all mobile phone calls, the results were similar. The association was independent of the cumulative call time and cumulative number of calls. However, our model used reported side of mobile phone use, which is potentially influenced by recall bias. The point process method provides an alternative to previously used epidemiologic research designs when one is including localization in the investigation of brain tumors and mobile phone use.
U2 - 10.1093/aje/kww082
DO - 10.1093/aje/kww082
M3 - Journal article
C2 - 27810856
SN - 0002-9262
VL - 184
SP - 818
EP - 828
JO - American Journal of Epidemiology
JF - American Journal of Epidemiology
IS - 11
ER -