The influence of anthropometry and body composition on children's bone health: The Childhood Health, Activity and Motor Performance School (The CHAMPS) Study, Denmark

TY - JOUR

T1 - The influence of anthropometry and body composition on children's bone health

T2 - The Childhood Health, Activity and Motor Performance School (The CHAMPS) Study, Denmark

AU - Heidemann, Malene

AU - Holst, René

AU - Schou, Anders J

AU - Klakk, Heidi

AU - Husby, Steffen

AU - Wedderkopp, Niels

AU - Mølgaard, Christian

N1 - CURIS 2015 NEXS 041

PY - 2015/2

Y1 - 2015/2

N2 - Overweight, physical inactivity and sedentary behaviour have become increasing problems during the past decade. Increased sedentary behaviour may change the body composition (BC) by increasing the fat mass relative to the lean mass (LM). These changes may influence bone health to describe how anthropometry and BC predict the development of the bone accruement. The longitudinal study is a part of The CHAMPS study-DK. Children were DXA scanned at baseline and at 2-year follow-up. BC (LM, BF %) and BMC, BMD and BA were measured. The relationship between bone traits, anthropometry and BC was analysed by multilevel regression analyses. Of the invited children, 742/800 (93 %) accepted to participate. Of these, 682/742 (92 %) participated at follow-up. Mean (range) of age at baseline was 9.5 years (7.7-12.1). Height, BMI, LM and BF % predicted bone mineral accrual and bone size positively and independently. Height and BMI are both positive predictors of bone accruement. LM is a more precise predictor of bone traits than BF % in both genders. The effects of height and BMI and LM on bone accruement are nearly identical in the two genders, while changes in BF % have different but positive effects on bone accretion in both boys and girls.

AB - Overweight, physical inactivity and sedentary behaviour have become increasing problems during the past decade. Increased sedentary behaviour may change the body composition (BC) by increasing the fat mass relative to the lean mass (LM). These changes may influence bone health to describe how anthropometry and BC predict the development of the bone accruement. The longitudinal study is a part of The CHAMPS study-DK. Children were DXA scanned at baseline and at 2-year follow-up. BC (LM, BF %) and BMC, BMD and BA were measured. The relationship between bone traits, anthropometry and BC was analysed by multilevel regression analyses. Of the invited children, 742/800 (93 %) accepted to participate. Of these, 682/742 (92 %) participated at follow-up. Mean (range) of age at baseline was 9.5 years (7.7-12.1). Height, BMI, LM and BF % predicted bone mineral accrual and bone size positively and independently. Height and BMI are both positive predictors of bone accruement. LM is a more precise predictor of bone traits than BF % in both genders. The effects of height and BMI and LM on bone accruement are nearly identical in the two genders, while changes in BF % have different but positive effects on bone accretion in both boys and girls.

U2 - 10.1007/s00223-014-9941-9

DO - 10.1007/s00223-014-9941-9

M3 - Journal article

C2 - 25539855

SN - 0171-967X

VL - 96

SP - 97

EP - 104

JO - Calcified Tissue International

JF - Calcified Tissue International

IS - 2

ER -