TY - JOUR
T1 - The impact of dysfunctional breathing on the assessment of asthma control
AU - Veidal, Sandra
AU - Jeppegaard, Maria
AU - Sverrild, Asger
AU - Backer, Vibeke
AU - Porsbjerg, Celeste
N1 - Copyright © 2016 Elsevier Ltd. All rights reserved.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - Background and objective Dysfunctional breathing (DB) is a respiratory disorder, which involves a pattern of breathing too deeply, too superficially and/or too rapidly. In asthma patients, DB may lead to an overestimation of the severity of asthma symptoms, and hence potentially to overtreatment. However, it is not known to which degree DB may affect estimates of asthma control, in a specialist clinical setting. Methods The MAPOut-study examined all patients referred consecutively over a 12-months period for specialist assessment of asthma at the Respiratory Outpatient Clinic at Bispebjerg Hospital in Copenhagen. All patients were examined with the Nijmegen questionnaire with a DB defined as a score ≥23 and the ACQ questionnaire. Linear regression analysis of predictors of ACQ score was performed. Asthma was defined as asthma symptoms and a positive asthma test. Results Of the 256 patients referred to the lung clinic, data on both the Nijmegen questionnaire and ACQ score was obtained in 127 patients, who were included in the present analysis. Median (range) age: 30 (15–63) years, and 76 (59.8%) were females. DB was found in 31 (24.4%). Asthmatic patients with co-existing DB had a poorer asthma control compared to asthmatics without DB (Median (range) ACQ score: 2.40 (0.20–4.60) vs 1.20 (0.00–4.40); p < 0.001.). A regression analysis showed that the effect of DB on asthma control was independent of airway hyperresponsiveness or airway inflammation in patients with DB. Conclusion Dysfunctional breathing is common among asthma patients in a specialist setting, and results in a clinically significant underestimation of asthma control, which may potentially lead to overtreatment.
AB - Background and objective Dysfunctional breathing (DB) is a respiratory disorder, which involves a pattern of breathing too deeply, too superficially and/or too rapidly. In asthma patients, DB may lead to an overestimation of the severity of asthma symptoms, and hence potentially to overtreatment. However, it is not known to which degree DB may affect estimates of asthma control, in a specialist clinical setting. Methods The MAPOut-study examined all patients referred consecutively over a 12-months period for specialist assessment of asthma at the Respiratory Outpatient Clinic at Bispebjerg Hospital in Copenhagen. All patients were examined with the Nijmegen questionnaire with a DB defined as a score ≥23 and the ACQ questionnaire. Linear regression analysis of predictors of ACQ score was performed. Asthma was defined as asthma symptoms and a positive asthma test. Results Of the 256 patients referred to the lung clinic, data on both the Nijmegen questionnaire and ACQ score was obtained in 127 patients, who were included in the present analysis. Median (range) age: 30 (15–63) years, and 76 (59.8%) were females. DB was found in 31 (24.4%). Asthmatic patients with co-existing DB had a poorer asthma control compared to asthmatics without DB (Median (range) ACQ score: 2.40 (0.20–4.60) vs 1.20 (0.00–4.40); p < 0.001.). A regression analysis showed that the effect of DB on asthma control was independent of airway hyperresponsiveness or airway inflammation in patients with DB. Conclusion Dysfunctional breathing is common among asthma patients in a specialist setting, and results in a clinically significant underestimation of asthma control, which may potentially lead to overtreatment.
KW - Adolescent
KW - Adult
KW - Asthma/complications
KW - Bronchial Provocation Tests/methods
KW - Cross-Sectional Studies
KW - Female
KW - Forced Expiratory Volume/physiology
KW - Glucocorticoids/therapeutic use
KW - Humans
KW - Hyperventilation/complications
KW - Male
KW - Middle Aged
KW - Severity of Illness Index
KW - Spirometry/methods
KW - Surveys and Questionnaires
KW - Treatment Outcome
KW - Vital Capacity/physiology
KW - Young Adult
U2 - 10.1016/j.rmed.2016.12.008
DO - 10.1016/j.rmed.2016.12.008
M3 - Journal article
C2 - 28137495
SN - 0954-6111
VL - 123
SP - 42
EP - 47
JO - Respiratory Medicine
JF - Respiratory Medicine
ER -