The immunological network: Novel approaches to the treatment of Crohn's disease

B. Davidsen; O. H. Nielsen; B. Vainer; I. Kirman

The immunological network: Novel approaches to the treatment of Crohn's disease

B. Davidsen, O. H. Nielsen^*, B. Vainer, I. Kirman

^*Corresponding author af dette arbejde

1 Citationer (Scopus)

Abstract

This article reviews experimental laboratory and preliminary clinical studies, which might lead to novel approaches in the treatment of Crohn's disease (CD). Some of the new agents might be of value for subgroups of CD patients, especially those who have been drug resistant to the 'classical therapy' with agents like glucocorticoids, mesalazine, azathioprine, 6-mercaptopurine, cyclosporin, and methotrexate. However, controlled trials for the novel agents mentioned in this review are highly warranted.

Originalsprog	Engelsk
Tidsskrift	Expert Opinion on Investigational Drugs
Vol/bind	5
Udgave nummer	5
Sider (fra-til)	555-564
Antal sider	10
ISSN	1354-3784
Status	Udgivet - 1 jan. 1996

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Citationsformater

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title = "The immunological network: Novel approaches to the treatment of Crohn's disease",

abstract = "This article reviews experimental laboratory and preliminary clinical studies, which might lead to novel approaches in the treatment of Crohn's disease (CD). Some of the new agents might be of value for subgroups of CD patients, especially those who have been drug resistant to the 'classical therapy' with agents like glucocorticoids, mesalazine, azathioprine, 6-mercaptopurine, cyclosporin, and methotrexate. However, controlled trials for the novel agents mentioned in this review are highly warranted.",

keywords = "Antibodies, Crohn's disease, Cytokines, Disease modulation, Immunology, Immunomodulation, Inflammation, Intestinal mucosa, Pharmacotherapeutics",

author = "B. Davidsen and Nielsen, {O. H.} and B. Vainer and I. Kirman",

year = "1996",

month = jan,

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language = "English",

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T2 - Novel approaches to the treatment of Crohn's disease

AU - Davidsen, B.

AU - Nielsen, O. H.

AU - Vainer, B.

AU - Kirman, I.

PY - 1996/1/1

Y1 - 1996/1/1

N2 - This article reviews experimental laboratory and preliminary clinical studies, which might lead to novel approaches in the treatment of Crohn's disease (CD). Some of the new agents might be of value for subgroups of CD patients, especially those who have been drug resistant to the 'classical therapy' with agents like glucocorticoids, mesalazine, azathioprine, 6-mercaptopurine, cyclosporin, and methotrexate. However, controlled trials for the novel agents mentioned in this review are highly warranted.

AB - This article reviews experimental laboratory and preliminary clinical studies, which might lead to novel approaches in the treatment of Crohn's disease (CD). Some of the new agents might be of value for subgroups of CD patients, especially those who have been drug resistant to the 'classical therapy' with agents like glucocorticoids, mesalazine, azathioprine, 6-mercaptopurine, cyclosporin, and methotrexate. However, controlled trials for the novel agents mentioned in this review are highly warranted.

KW - Antibodies

KW - Crohn's disease

KW - Cytokines

KW - Disease modulation

KW - Immunology

KW - Immunomodulation

KW - Inflammation

KW - Intestinal mucosa

KW - Pharmacotherapeutics

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M3 - Review

AN - SCOPUS:0029994839

SN - 1354-3784

VL - 5

SP - 555

EP - 564

JO - Current Opinion in Investigational Drugs

JF - Current Opinion in Investigational Drugs

IS - 5

ER -

The immunological network: Novel approaches to the treatment of Crohn's disease

Abstract

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