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The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)
Maria Hotoft Michaelsen, Kishor M. Wasan, Olena Sivak,
Anette Mullertz
,
Thomas Rades
28
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Keyphrases
Self-nanoemulsifying Drug Delivery Systems (SNEDDS)
100%
Drug Loading
100%
Digestion
100%
Orlistat
21%
In Vitro Lipolysis
5%
Lipid Digestion
5%
I(1)
5%
Lipase Inhibitor
5%
Rat Model
5%
Drug Precipitation
5%
Equilibrium Solubility
5%
In Vitro Digestion
5%
Oral Absorption
5%
Drug Absorption
5%
Soybean Oil
5%
Tmax
5%
Poorly Water-soluble Drugs
5%
Ethanol
5%
Cmax
5%
Pharmacokinetic Parameters
5%
System Concept
5%
Kolliphor RH40
5%
Pharmacology, Toxicology and Pharmaceutical Science
Drug Delivery System
100%
Halofantrine
100%
Tetrahydrolipstatin
26%
Bioavailability
10%
Rat Model
5%
Pharmacokinetic Parameter
5%
Esterase Inhibitor
5%