The effect of alginates on in vitro gastric digestion of particulated whey protein

TY - JOUR

T1 - The effect of alginates on in vitro gastric digestion of particulated whey protein

AU - Koutina, Glykeria

AU - Ioannidi, Eleni

AU - Melo Nogueira, Barbara

AU - Ipsen, Richard

PY - 2018/5

Y1 - 2018/5

N2 - The aim of the study was to investigate how microparticulated and nanoparticulated whey proteins mixed with alginate respond to simulated in vitro gastric digestion conditions at pH 3.0. Initially, particle size distributions and zeta potential were measured in all mixtures at pH 3.0. Particle size distributions as well as SDS-PAGE were used to investigate the rate of protein degradation by pepsin during simulated in vitro gastric digestion. The complexation of nanoparticulated and microparticulated whey protein with alginates causes formation of insoluble and soluble complexes, which can resist pepsin degradation to a different degree. These results highlight the potential of developing new food products, which can enhance satiety.

AB - The aim of the study was to investigate how microparticulated and nanoparticulated whey proteins mixed with alginate respond to simulated in vitro gastric digestion conditions at pH 3.0. Initially, particle size distributions and zeta potential were measured in all mixtures at pH 3.0. Particle size distributions as well as SDS-PAGE were used to investigate the rate of protein degradation by pepsin during simulated in vitro gastric digestion. The complexation of nanoparticulated and microparticulated whey protein with alginates causes formation of insoluble and soluble complexes, which can resist pepsin degradation to a different degree. These results highlight the potential of developing new food products, which can enhance satiety.

U2 - 10.1111/1471-0307.12458

DO - 10.1111/1471-0307.12458

M3 - Journal article

SN - 1364-727X

VL - 77

SP - 469

EP - 477

JO - International Journal of Dairy Technology

JF - International Journal of Dairy Technology

IS - 2

ER -