The broad-spectrum metalloproteinase inhibitor BB-94 inhibits growth, HER3 and Erk activation in fulvestrant-resistant breast cancer cell lines

Medicin og biovidenskab

• batimastat 100%
• Breast Neoplasms 37%
• Canertinib 10%
• Cell Line 34%
• Conditioned Culture Medium 5%
• ErbB Receptors 5%
• Estrogen Receptor Modulators 13%
• Estrogen Receptors 5%
• Fulvestrant 78%
• Gefitinib 6%
• Growth 29%
• Ligands 30%
• MCF-7 Cells 23%
• Metalloproteases 63%
• N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide 8%
• Neuregulin-1 7%
• Phosphorylation 11%
• TAPI-2 21%