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The anticonvulsant retigabine suppresses neuronal Kv2-mediated currents
Jeroen I Stas, Elke Bocksteins, Camilla S Jensen,
Nicole Schmitt
, Dirk J Snyders
Physiology of circulation, kidney and lung
13
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73
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Keyphrases
Retigabine
100%
Anticonvulsant
100%
Kv7.2
28%
Kv2.1
28%
Neuroprotective Properties
28%
Kv2.1 Channel
28%
Channel Function
14%
Molecular Targets
14%
Hyperexcitability
14%
Kv7.5
14%
Off-target Effects
14%
Cultured Hippocampal Neurons
14%
Conductance
14%
Mammalian Expression System
14%
Kv7 Channels
14%
KCNE2
14%
Epilepsy
14%
M-current
14%
Kv7.3
14%
Prolonged Exposure
14%
Channel Openers
14%
Apoptosis
14%
Related Disorders
14%
Neuroscience
Retigabine
100%
Anticonvulsant
100%
Neuroprotective Agent
28%
KCNE2
14%
Potassium Channel KCNQ5
14%
Gene Expression System
14%
Programmed Cell Death
14%
Pharmacology, Toxicology and Pharmaceutical Science
Retigabine
100%
Anticonvulsive Agent
100%
Neuroprotective Agent
28%
Potassium Channel KCNQ5
14%
Long Term Exposure
14%
Channel Opener
14%
Molecular Target
14%