The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro

Cecilie Hurup Munkboel; Lise Rudbaek Christensen; Julie Islin; Silvia Bonomo; Lars Olsen; Flemming Steen Jorgensen; Bjarne Styrishave

doi:10.1093/biolre/ioy098

The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro

Cecilie Hurup Munkboel, Lise Rudbaek Christensen, Julie Islin, Silvia Bonomo, Lars Olsen, Flemming Steen Jorgensen, Bjarne Styrishave

1 Citationer (Scopus)

Originalsprog	Engelsk
Tidsskrift	Biology of Reproduction
Vol/bind	99
Udgave nummer	4
Sider (fra-til)	888-897
ISSN	0006-3363
DOI	https://doi.org/10.1093/biolre/ioy098
Status	Udgivet - 1 okt. 2018

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10.1093/biolre/ioy098

ioy098.pdfForlagets udgivne version, 2,71 MB

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@article{fe94f828f2334ca89d29cbf033581e7e,

title = "The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro",

keywords = "in vitro, H295R, molecular dynamics, endocrine disrupting drug, steroidogenesis, CYP19A1, CYP21A2",

author = "Munkboel, {Cecilie Hurup} and Christensen, {Lise Rudbaek} and Julie Islin and Silvia Bonomo and Lars Olsen and Jorgensen, {Flemming Steen} and Bjarne Styrishave",

year = "2018",

month = oct,

day = "1",

doi = "10.1093/biolre/ioy098",

language = "English",

volume = "99",

pages = "888--897",

journal = "Biology of Reproduction",

issn = "0006-3363",

publisher = "Society for the Study of Reproduction",

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TY - JOUR

T1 - The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro

AU - Munkboel, Cecilie Hurup

AU - Christensen, Lise Rudbaek

AU - Islin, Julie

AU - Bonomo, Silvia

AU - Olsen, Lars

AU - Jorgensen, Flemming Steen

AU - Styrishave, Bjarne

PY - 2018/10/1

Y1 - 2018/10/1

KW - in vitro

KW - H295R

KW - molecular dynamics

KW - endocrine disrupting drug

KW - steroidogenesis

KW - CYP19A1

KW - CYP21A2

U2 - 10.1093/biolre/ioy098

DO - 10.1093/biolre/ioy098

M3 - Journal article

C2 - 29718108

SN - 0006-3363

VL - 99

SP - 888

EP - 897

JO - Biology of Reproduction

JF - Biology of Reproduction

IS - 4

ER -

The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro

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