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The -14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1a binding site and increases lactase promoter activity
Tine G K Jensen, Anke Liebert, Rikke Lewinsky, Dallas M Swallow,
Jørgen Olsen
, Jesper T Troelsen
Glycomics Program
Institut for Cellulær og Molekylær Medicin
34
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Alfabetisk
Biochemistry, Genetics and Molecular Biology
Lactase
100%
Promoter Region
100%
Binding Site
100%
Enhancer Region
44%
Allele
22%
Electrophoretic Mobility-Shift Assay
11%
Binding Affinity
11%
Transfection
11%
Single-Nucleotide Polymorphism
11%
Neuroscience
Promoter Region
100%
Lactase
100%
Binding Site
100%
Enhancer Region
44%
Binding Affinity
11%
Transfection
11%
Single-Nucleotide Polymorphism
11%
Agricultural and Biological Sciences
Allele
100%
Single Nucleotide Polymorphism
50%
Transfection
50%
Keyphrases
Intestinal Lactase
20%
Strong Enhancer
20%
Immunology and Microbiology
Electrophoretic Mobility-Shift Assay
25%