TY - JOUR
T1 - Tetramethoxy-aminorhodamine (TMARh)
T2 - a bichromophore, an improved fluorophore, and a pH-switch
AU - Sørensen, Thomas Just
AU - Shi, Dong
AU - Laursen, Bo Wegge
PY - 2016/5/17
Y1 - 2016/5/17
N2 - Rhodamine is one of the most widely used fluorescent dyes. Here, a new synthetic pathway to the popular dyes is reported and the effect of adding four methoxy groups to the molecular structure is investigated. Tetramethoxy-aminorhodamine (TMARh) is found to show superior pH switching compared to the rhodamine without the four methoxy groups, owing to changed properties of the dark "off" state and increased fluorescence intensity in the protonated "on" state.
AB - Rhodamine is one of the most widely used fluorescent dyes. Here, a new synthetic pathway to the popular dyes is reported and the effect of adding four methoxy groups to the molecular structure is investigated. Tetramethoxy-aminorhodamine (TMARh) is found to show superior pH switching compared to the rhodamine without the four methoxy groups, owing to changed properties of the dark "off" state and increased fluorescence intensity in the protonated "on" state.
U2 - 10.1002/chem.201600496
DO - 10.1002/chem.201600496
M3 - Letter
C2 - 26995766
SN - 1521-3765
VL - 22
SP - 7046
EP - 7049
JO - Chemistry: A European Journal
JF - Chemistry: A European Journal
IS - 21
ER -