Terapeutiske vacciner er et nyt behandlings-princip ved kastrationsresistent prostatacancer

Sissal Sigmundsdòttir Djurhuus, Klaus Brasso, Kasper Drimer Berg, Peter Iversen, Martin Andreas Røder

Abstract

Therapeutic vaccines is a novel approach in castration-resistant prostate cancer treatment

Castration-resistant prostate cancer (CRPC) is defined as tumour progression despite castrate levels of serum testosterone. During the past decade a number of new therapies, including chemo­therapy and novel endocrine agents have been approved for CRPC treatment. The continued need for new effective drugs in CRPC has led to development of a novel therapeutic approach in CRPC treatment. Therapeutic vaccines activate the immune system to kill prostate cancer cells. This review describes recent pivotal phase 2 and 3 trials of CRPC vaccines and discusses the impact on future CRPC management.
Bidragets oversatte titelTherapeutic vaccines is a novel approach in castration-resistant prostate cancer treatment
OriginalsprogDansk
Artikelnummer22
TidsskriftUgeskrift for Laeger
Vol/bind177
Udgave nummer22
Sider (fra-til)2-7
Antal sider6
ISSN0041-5782
StatusUdgivet - 11 maj 2015

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