Temporal trends in survival after out-of-hospital cardiac arrest in patients with and without underlying chronic obstructive pulmonary disease

Sidsel G Møller; Shahzleen Rajan; Fredrik Folke; Carolina Malta Hansen; Steen Møller Hansen; Kristian Kragholm; Freddy K Lippert; Lena Karlsson; Lars Køber; Christian Torp-Pedersen; Gunnar H Gislason; Mads Wissenberg

doi:10.1016/j.resuscitation.2016.04.017

Temporal trends in survival after out-of-hospital cardiac arrest in patients with and without underlying chronic obstructive pulmonary disease

Sidsel G Møller, Shahzleen Rajan, Fredrik Folke, Carolina Malta Hansen, Steen Møller Hansen, Kristian Kragholm, Freddy K Lippert, Lena Karlsson, Lars Køber, Christian Torp-Pedersen, Gunnar H Gislason, Mads Wissenberg

Institut for Klinisk Medicin

5 Citationer (Scopus)

Abstract

Aim: Survival after out-of-hospital cardiac arrest (OHCA) has tripled during the past decade in Denmark as a likely result of improvements in cardiac arrest management. This study analyzed whether these improvements were applicable for patients with chronic obstructive pulmonary disease (COPD). Methods: Patients ≥18 years with OHCA of presumed cardiac cause were identified through the Danish Cardiac Arrest Registry, 2001-2011. Patients with a history of COPD up to ten years prior to arrest were identified from the Danish National Patient Register and compared to non-COPD patients. Results: Of 21,480 included patients, 3056 (14.2%) had history of COPD. Compared to non-COPD patients, COPD patients were older (75 vs. 71 years), less likely male (61.2% vs. 68.5%), had higher prevalence of other comorbidities, and were less likely to have: arrests outside private homes (17.7% vs. 28.3%), witnessed arrests (48.7% vs. 52.9%), bystander cardiopulmonary resuscitation (25.8% vs. 34.8%), and shockable heart rhythm (15.6% vs. 29.9%), all p < 0.001; while no significant difference in the time-interval from recognition of arrest to rhythm analysis by ambulance-crew; p = 0.24. From 2001 to 2011, survival upon hospital arrival increased in both patient-groups (from 6.8% to 17.1% in COPD patients and from 8.2% to 25.6% in non-COPD patients, p < 0.001). However, no significant change was observed in 30-day survival in COPD patients (from 3.7% to 2.1%, p = 0.27), in contrast to non-COPD patients (from 3.5% to 13.0%, p < 0.001). Conclusions: Despite generally improved 30-day survival after OHCA over time, no improvement was observed in 30-day survival in COPD patients.

Originalsprog	Engelsk
Tidsskrift	Resuscitation
Vol/bind	104
Sider (fra-til)	76-82
Antal sider	7
ISSN	0300-9572
DOI	https://doi.org/10.1016/j.resuscitation.2016.04.017
Status	Udgivet - 1 jul. 2016

Adgang til dokumentet

10.1016/j.resuscitation.2016.04.017

Citationsformater

Møller, S. G., Rajan, S., Folke, F., Malta Hansen, C., Hansen, S. M., Kragholm, K., Lippert, F. K., Karlsson, L., Køber, L., Torp-Pedersen, C., Gislason, G. H., & Wissenberg, M. (2016). Temporal trends in survival after out-of-hospital cardiac arrest in patients with and without underlying chronic obstructive pulmonary disease. Resuscitation, 104, 76-82. https://doi.org/10.1016/j.resuscitation.2016.04.017

Møller, SG, Rajan, S, Folke, F, Malta Hansen, C, Hansen, SM, Kragholm, K, Lippert, FK, Karlsson, L, Køber, L, Torp-Pedersen, C, Gislason, GH & Wissenberg, M 2016, 'Temporal trends in survival after out-of-hospital cardiac arrest in patients with and without underlying chronic obstructive pulmonary disease', Resuscitation, bind 104, s. 76-82. https://doi.org/10.1016/j.resuscitation.2016.04.017

@article{42b9722d479445a29a2e51cfb775e06a,

title = "Temporal trends in survival after out-of-hospital cardiac arrest in patients with and without underlying chronic obstructive pulmonary disease",

abstract = "Aim: Survival after out-of-hospital cardiac arrest (OHCA) has tripled during the past decade in Denmark as a likely result of improvements in cardiac arrest management. This study analyzed whether these improvements were applicable for patients with chronic obstructive pulmonary disease (COPD). Methods: Patients ≥18 years with OHCA of presumed cardiac cause were identified through the Danish Cardiac Arrest Registry, 2001-2011. Patients with a history of COPD up to ten years prior to arrest were identified from the Danish National Patient Register and compared to non-COPD patients. Results: Of 21,480 included patients, 3056 (14.2%) had history of COPD. Compared to non-COPD patients, COPD patients were older (75 vs. 71 years), less likely male (61.2% vs. 68.5%), had higher prevalence of other comorbidities, and were less likely to have: arrests outside private homes (17.7% vs. 28.3%), witnessed arrests (48.7% vs. 52.9%), bystander cardiopulmonary resuscitation (25.8% vs. 34.8%), and shockable heart rhythm (15.6% vs. 29.9%), all p < 0.001; while no significant difference in the time-interval from recognition of arrest to rhythm analysis by ambulance-crew; p = 0.24. From 2001 to 2011, survival upon hospital arrival increased in both patient-groups (from 6.8% to 17.1% in COPD patients and from 8.2% to 25.6% in non-COPD patients, p < 0.001). However, no significant change was observed in 30-day survival in COPD patients (from 3.7% to 2.1%, p = 0.27), in contrast to non-COPD patients (from 3.5% to 13.0%, p < 0.001). Conclusions: Despite generally improved 30-day survival after OHCA over time, no improvement was observed in 30-day survival in COPD patients.",

keywords = "Journal Article",

author = "M{\o}ller, {Sidsel G} and Shahzleen Rajan and Fredrik Folke and {Malta Hansen}, Carolina and Hansen, {Steen M{\o}ller} and Kristian Kragholm and Lippert, {Freddy K} and Lena Karlsson and Lars K{\o}ber and Christian Torp-Pedersen and Gislason, {Gunnar H} and Mads Wissenberg",

year = "2016",

month = jul,

day = "1",

doi = "10.1016/j.resuscitation.2016.04.017",

language = "English",

volume = "104",

pages = "76--82",

journal = "Resuscitation",

issn = "0300-9572",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Temporal trends in survival after out-of-hospital cardiac arrest in patients with and without underlying chronic obstructive pulmonary disease

AU - Møller, Sidsel G

AU - Rajan, Shahzleen

AU - Folke, Fredrik

AU - Malta Hansen, Carolina

AU - Hansen, Steen Møller

AU - Kragholm, Kristian

AU - Lippert, Freddy K

AU - Karlsson, Lena

AU - Køber, Lars

AU - Torp-Pedersen, Christian

AU - Gislason, Gunnar H

AU - Wissenberg, Mads

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Aim: Survival after out-of-hospital cardiac arrest (OHCA) has tripled during the past decade in Denmark as a likely result of improvements in cardiac arrest management. This study analyzed whether these improvements were applicable for patients with chronic obstructive pulmonary disease (COPD). Methods: Patients ≥18 years with OHCA of presumed cardiac cause were identified through the Danish Cardiac Arrest Registry, 2001-2011. Patients with a history of COPD up to ten years prior to arrest were identified from the Danish National Patient Register and compared to non-COPD patients. Results: Of 21,480 included patients, 3056 (14.2%) had history of COPD. Compared to non-COPD patients, COPD patients were older (75 vs. 71 years), less likely male (61.2% vs. 68.5%), had higher prevalence of other comorbidities, and were less likely to have: arrests outside private homes (17.7% vs. 28.3%), witnessed arrests (48.7% vs. 52.9%), bystander cardiopulmonary resuscitation (25.8% vs. 34.8%), and shockable heart rhythm (15.6% vs. 29.9%), all p < 0.001; while no significant difference in the time-interval from recognition of arrest to rhythm analysis by ambulance-crew; p = 0.24. From 2001 to 2011, survival upon hospital arrival increased in both patient-groups (from 6.8% to 17.1% in COPD patients and from 8.2% to 25.6% in non-COPD patients, p < 0.001). However, no significant change was observed in 30-day survival in COPD patients (from 3.7% to 2.1%, p = 0.27), in contrast to non-COPD patients (from 3.5% to 13.0%, p < 0.001). Conclusions: Despite generally improved 30-day survival after OHCA over time, no improvement was observed in 30-day survival in COPD patients.

AB - Aim: Survival after out-of-hospital cardiac arrest (OHCA) has tripled during the past decade in Denmark as a likely result of improvements in cardiac arrest management. This study analyzed whether these improvements were applicable for patients with chronic obstructive pulmonary disease (COPD). Methods: Patients ≥18 years with OHCA of presumed cardiac cause were identified through the Danish Cardiac Arrest Registry, 2001-2011. Patients with a history of COPD up to ten years prior to arrest were identified from the Danish National Patient Register and compared to non-COPD patients. Results: Of 21,480 included patients, 3056 (14.2%) had history of COPD. Compared to non-COPD patients, COPD patients were older (75 vs. 71 years), less likely male (61.2% vs. 68.5%), had higher prevalence of other comorbidities, and were less likely to have: arrests outside private homes (17.7% vs. 28.3%), witnessed arrests (48.7% vs. 52.9%), bystander cardiopulmonary resuscitation (25.8% vs. 34.8%), and shockable heart rhythm (15.6% vs. 29.9%), all p < 0.001; while no significant difference in the time-interval from recognition of arrest to rhythm analysis by ambulance-crew; p = 0.24. From 2001 to 2011, survival upon hospital arrival increased in both patient-groups (from 6.8% to 17.1% in COPD patients and from 8.2% to 25.6% in non-COPD patients, p < 0.001). However, no significant change was observed in 30-day survival in COPD patients (from 3.7% to 2.1%, p = 0.27), in contrast to non-COPD patients (from 3.5% to 13.0%, p < 0.001). Conclusions: Despite generally improved 30-day survival after OHCA over time, no improvement was observed in 30-day survival in COPD patients.

KW - Journal Article

U2 - 10.1016/j.resuscitation.2016.04.017

DO - 10.1016/j.resuscitation.2016.04.017

M3 - Journal article

C2 - 27164010

SN - 0300-9572

VL - 104

SP - 76

EP - 82

JO - Resuscitation

JF - Resuscitation

ER -

Temporal trends in survival after out-of-hospital cardiac arrest in patients with and without underlying chronic obstructive pulmonary disease

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater