TY - JOUR
T1 - Temporal trends in atrial fibrillation recurrence rates after ablation between 2005 and 2014
T2 - a nationwide Danish cohort study
AU - Pallisgaard, Jannik Langtved
AU - Gislason, Gunnar Hilmar
AU - Hansen, Jim
AU - Johannessen, Arne
AU - Torp-Pedersen, Christian
AU - Rasmussen, Peter Vibe
AU - Hansen, Morten Lock
PY - 2018/2/7
Y1 - 2018/2/7
N2 - Aims During the last decade, ablation has increasingly been used in rhythm control management of patients with atrial fibrillation (AF). Over time, experience and techniques have improved and indications for ablation have expanded. The purpose of this study was to investigate whether the recurrence rate of AF following ablation has improved during last decade. Methods and results Through Danish nationwide registers, all patients with first-Time AF ablation, between 2005 and 2014 in Denmark were identified. Recurrent AF after ablation was identified with 1 year follow-up. A total of 5425 patients undergoing first-Time ablation were included. While patient median age increased over time the median AF duration prior to ablation decreased. The rates of recurrent AF decreased from 45% in 2005-2006 to 31% 2013-2014 with the relative risk of recurrent AF almost halved with an odds ratio of 0.57 [95% confidence intervals (95% CI) 0.47-0.68] in 2013- 2014 compared with patients undergoing ablation in 2005-2006. Female gender, hypertension, AF duration >2 years, and cardioversion within 1 year prior to ablation were all associated with an increased risk of recurrent AF. Conclusion One year risk of recurrent AF following first-Time ablation has almost halved from 2006 to 2014. Hypertension, female sex, cardioversion 1 year prior to ablation, and AF duration for more than 2 years all increased the associated risk of recurrent AF. All rights reserved.
AB - Aims During the last decade, ablation has increasingly been used in rhythm control management of patients with atrial fibrillation (AF). Over time, experience and techniques have improved and indications for ablation have expanded. The purpose of this study was to investigate whether the recurrence rate of AF following ablation has improved during last decade. Methods and results Through Danish nationwide registers, all patients with first-Time AF ablation, between 2005 and 2014 in Denmark were identified. Recurrent AF after ablation was identified with 1 year follow-up. A total of 5425 patients undergoing first-Time ablation were included. While patient median age increased over time the median AF duration prior to ablation decreased. The rates of recurrent AF decreased from 45% in 2005-2006 to 31% 2013-2014 with the relative risk of recurrent AF almost halved with an odds ratio of 0.57 [95% confidence intervals (95% CI) 0.47-0.68] in 2013- 2014 compared with patients undergoing ablation in 2005-2006. Female gender, hypertension, AF duration >2 years, and cardioversion within 1 year prior to ablation were all associated with an increased risk of recurrent AF. Conclusion One year risk of recurrent AF following first-Time ablation has almost halved from 2006 to 2014. Hypertension, female sex, cardioversion 1 year prior to ablation, and AF duration for more than 2 years all increased the associated risk of recurrent AF. All rights reserved.
KW - Journal Article
U2 - 10.1093/eurheartj/ehx466
DO - 10.1093/eurheartj/ehx466
M3 - Journal article
C2 - 29020388
SN - 0195-668X
VL - 39
SP - 442
EP - 449
JO - European Heart Journal
JF - European Heart Journal
IS - 6
ER -