TY - JOUR
T1 - Syphilis screening practices in blood transfusion facilities in Ghana
AU - Sarkodie, Francis
AU - Hassall, Oliver
AU - Owusu-Dabo, Ellis
AU - Owusu-Ofori, Shirley
AU - Bates, Imelda
AU - Bygbjerg, Ib C.
AU - Ansah, Justina Kordai
AU - Ullum, Henrik
N1 - Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - OBJECTIVES: The primary objective of this study was to compare laboratory practices for screening blood donors for syphilis at blood transfusion facilities in Ghana with the recommendations of the World Health Organization and the National Blood Service, Ghana (NBSG). The prevalence of syphilis antibodies in blood donors in Ghana was also estimated.METHODS: Over an 11-month period, from February 2014 to January 2015, a semi-structured questionnaire was administered to 122 laboratory technical heads out of a total of 149 transfusion facilities in Ghana. The response rate was 81.9%.RESULTS: A total of 58 (48%) transfusion facilities tested donors for syphilis, with an estimated 3.7% seroprevalence (95% confidence interval 3.6-3.8%). A total of 62782 out of 91386 (68.7%) donations were tested with assays that are not recommended. The estimated syphilis seroprevalence in voluntary donations was 2.9%, compared to 4.0% in family donations (p=0.001). Only 6.9% of the health facilities were using standard operating procedures (SOPs).CONCLUSIONS: Despite international and national recommendations, more than half of the studied health facilities that provide blood transfusions in Ghana are not screening blood donations for syphilis. These data show a considerable mismatch between recommendations and practice, with serious consequences for blood safety and public health.
AB - OBJECTIVES: The primary objective of this study was to compare laboratory practices for screening blood donors for syphilis at blood transfusion facilities in Ghana with the recommendations of the World Health Organization and the National Blood Service, Ghana (NBSG). The prevalence of syphilis antibodies in blood donors in Ghana was also estimated.METHODS: Over an 11-month period, from February 2014 to January 2015, a semi-structured questionnaire was administered to 122 laboratory technical heads out of a total of 149 transfusion facilities in Ghana. The response rate was 81.9%.RESULTS: A total of 58 (48%) transfusion facilities tested donors for syphilis, with an estimated 3.7% seroprevalence (95% confidence interval 3.6-3.8%). A total of 62782 out of 91386 (68.7%) donations were tested with assays that are not recommended. The estimated syphilis seroprevalence in voluntary donations was 2.9%, compared to 4.0% in family donations (p=0.001). Only 6.9% of the health facilities were using standard operating procedures (SOPs).CONCLUSIONS: Despite international and national recommendations, more than half of the studied health facilities that provide blood transfusions in Ghana are not screening blood donations for syphilis. These data show a considerable mismatch between recommendations and practice, with serious consequences for blood safety and public health.
KW - Antibodies, Bacterial
KW - Blood Donors
KW - Blood Safety
KW - Blood Transfusion
KW - Ghana
KW - Humans
KW - Seroepidemiologic Studies
KW - Surveys and Questionnaires
KW - Syphilis
KW - Syphilis Serodiagnosis
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
U2 - 10.1016/j.ijid.2015.12.020
DO - 10.1016/j.ijid.2015.12.020
M3 - Journal article
C2 - 26751240
SN - 1201-9712
VL - 43
SP - 90
EP - 94
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
ER -
